{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:20:00Z","timestamp":1740126000102,"version":"3.37.3"},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T00:00:00Z","timestamp":1498003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Nicolaides\u2013Baraitser Syndrome(<jats:styled-content style=\"fixed-case\">NCBRS<\/jats:styled-content>) is an extremely rare condition which has been reported in only a few cases. <jats:styled-content style=\"fixed-case\">NCBRS<\/jats:styled-content> is a distinct clinical condition with typical clinical features of pre\u2010 and post\u2010natal global developmental delay, impaired speech, and seizures. Microcephaly, sparse hair, anteverted alae nasi, undefined philtrum, prominence of distal phalanges and interphalangeal joints, and short metacarpals are also typical of <jats:styled-content style=\"fixed-case\">NCBRS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>There are no reported cases in the literature of patients with <jats:styled-content style=\"fixed-case\">NCBRS<\/jats:styled-content> presenting with multiple dental impactions, and to the authors\u2019 knowledge, this is the 28th fully documented case of <jats:styled-content style=\"fixed-case\">NCBRS<\/jats:styled-content> and only 75 cases identified as potentially having <jats:styled-content style=\"fixed-case\">NCBRS<\/jats:styled-content>. The clinical features, diagnosis, and course of management are also described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although <jats:styled-content style=\"fixed-case\">NCBRS<\/jats:styled-content> is very rare, it is important to assess dental development in view of the possibility of multiple supernumerary teeth which can have detrimental effects on the occlusion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.12309","type":"journal-article","created":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T07:12:46Z","timestamp":1498029166000},"page":"583-587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Supernumeraries in Nicolaides\u2013Baraitser Syndrome"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7001-9546","authenticated-orcid":false,"given":"Bouthayna","family":"Al\u2010Tamimi","sequence":"first","affiliation":[{"name":"Dental and Maxillofacial Department Great Ormond Street Hospital for Children London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Abela","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Guy's and St Thomas\u2019 NHS Foundation Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huw G.","family":"Jeremiah","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Barts and The Royal London Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert D.","family":"Evans","sequence":"additional","affiliation":[{"name":"Dental and Maxillofacial Department Great Ormond Street Hospital for Children London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.1105"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019605-199307000-00007"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32956"},{"key":"e_1_2_8_5_1","first-page":"245","article-title":"Mental retardation, sparse hair, facial dysmorphism with a prominent lower lip, and lipodystrophy: a variant example of Nicolaides\u2013Baraitser syndrome?","volume":"14","author":"Witters I","year":"2003","journal-title":"Genet Couns"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019605-200310000-00005"},{"key":"e_1_2_8_7_1","first-page":"450","article-title":"Supernumerary premolars: a literature review","volume":"26","author":"Solares R","year":"2004","journal-title":"Paediatr Dent"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2009.1177"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345010800110501"},{"key":"e_1_2_8_10_1","first-page":"463","article-title":"Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: non\u2010dividing cells express growth stimulating Fgf\u20104 gene","volume":"38","author":"Jernvall J","year":"1994","journal-title":"Int J Dev Biol"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.9.4520"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2003.12.019"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2008.02.135"}],"container-title":["International Journal of Paediatric Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fipd.12309","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ipd.12309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T08:47:22Z","timestamp":1695977242000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ipd.12309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,21]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/ipd.12309"],"URL":"https:\/\/doi.org\/10.1111\/ipd.12309","archive":["Portico"],"relation":{},"ISSN":["0960-7439","1365-263X"],"issn-type":[{"type":"print","value":"0960-7439"},{"type":"electronic","value":"1365-263X"}],"subject":[],"published":{"date-parts":[[2017,6,21]]},"assertion":[{"value":"2017-06-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}