{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T11:15:30Z","timestamp":1759058130567,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T00:00:00Z","timestamp":1539043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The eruption of primary teeth represents a stage of many challenges for parents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the occurrence of signs and symptoms related to the eruption of the primary dentition in children with congenital Zika syndrome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Longitudinal study developed with 79 children followed up for a period of 24\u00a0months. Data on sex, gestational age, low birthweight, microcephaly, signs and symptoms related to the dental eruption phase, and use and type of medication were collected. Data were presented by descriptive and inferential statistics (chi\u2010square test).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The majority (94.9%) exhibited simultaneously two or more signs and symptoms related to dental eruption. Increased salivation (91.1%), irritability (86.1%), and gingival itching (83.5%) were the most commonly reported signs and symptoms. Bivariate analysis showed association between elevation of body temperature and sex (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). Almost two\u2010thirds of mothers (63.3%) reported using medication to relieve symptoms presented by the child; however, the use of topical medication prevailed (57.1%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>All children with congenital Zika syndrome presented manifestations related to the eruption of primary teeth, with increased salivation, irritability, and gingival pruritus. The use of ointments and gels was the option of mothers in the treatment of the oral discomfort presented by infants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.12431","type":"journal-article","created":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T05:51:27Z","timestamp":1539150687000},"page":"74-78","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Teething symptoms in children with congenital Zika syndrome: A 2\u2010year follow\u2010up"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7779-2478","authenticated-orcid":false,"given":"Alidianne F\u00e1bia Cabral","family":"Cavalcanti","sequence":"first","affiliation":[{"name":"Post\u2010graduate Program in Dentistry State University of Para\u00edba Campina Grande Paraiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y\u00easka Paola Costa","family":"Aguiar","sequence":"additional","affiliation":[{"name":"Post\u2010graduate Program in Dentistry State University of Para\u00edba Campina Grande Paraiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana Suely","family":"de Oliveira Melo","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Federal University of Campina Grande Campina Grande Paraiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeime Iara Bezerra","family":"de Freitas Leal","sequence":"additional","affiliation":[{"name":"Specialized Center for Rehabilitation Campina Grande Paraiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro Leite","family":"Cavalcanti","sequence":"additional","affiliation":[{"name":"Post\u2010graduate Program in Dentistry State University of Para\u00edba Campina Grande Paraiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio d\u2019\u00c1vila Lins Bezerra","family":"Cavalcanti","sequence":"additional","affiliation":[{"name":"Post\u2010graduate Program in Dentistry State University of Para\u00edba Campina Grande Paraiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4034\/1519.0501.2010.0102.0006"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-3501"},{"key":"e_1_2_10_4_1","first-page":"54","article-title":"Guideline on perinatal and infant oral health care","volume":"38","author":"American Academy of Pediatric Dentistry","year":"2016","journal-title":"Pediatr Dent"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4034\/PBOCI.2015.151.23"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.34.3.h318882h52616225"},{"key":"e_1_2_10_7_1","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1542\/peds.2010-2697","article-title":"Prospective longitudinal study of signs and symptoms associated with primary tooth eruption","volume":"128","author":"Ramos\u2010Jorge J","year":"2011","journal-title":"Pediatrics"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-237X.214553"},{"key":"e_1_2_10_9_1","first-page":"e3982","article-title":"Chronology of the first deciduous tooth eruption in Brazilian children with microcephaly associated with zika virus: a longitudinal study","volume":"18","author":"Aguiar YPC","year":"2018","journal-title":"Pesqui Bras Odontopediatria Clin Integr"},{"volume-title":"Assessment of Infants with Microcephaly in the Context of Zika Virus \u2010 Interim Guidance \u2010 4 March 2016","year":"2016","author":"World Health Organization (WHO)","key":"e_1_2_10_10_1"},{"volume-title":"Protocolo de Vigil\u00e2ncia e Resposta \u00e0 Ocorr\u00eancia de Microcefalia e\/ou Altera\u00e7\u00f5es do Sistema Nervoso Central (SNC). 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