{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T16:02:15Z","timestamp":1760889735186,"version":"3.37.3"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T00:00:00Z","timestamp":1544572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The anatomical and morphological alterations associated with cleft lip and palate (<jats:styled-content style=\"fixed-case\">CLP<\/jats:styled-content>) favour the buildup of dental plaque.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the efficacy of a new add\u2010on to regular toothbrush\u2014the Cleft Toothbrush, in removing the dental plaque of <jats:styled-content style=\"fixed-case\">CLP<\/jats:styled-content> patients, compared to a regular toothbrush.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Forty\u2010five children with <jats:styled-content style=\"fixed-case\">CLP<\/jats:styled-content> were randomly organized into two groups: A (n\u00a0=\u00a026, 2\u20106\u00a0years old) and B (n\u00a0=\u00a019, 7\u201012\u00a0years old). They were evaluated at days 0, 15, 30, and 60. After brushing their teeth with a regular toothbrush or with the Cleft Toothbrush, the dental plaque was recorded using an adapted Plaque Index (<jats:styled-content style=\"fixed-case\">aPI<\/jats:styled-content>). Data analyses were performed in <jats:styled-content style=\"fixed-case\">IBM SPSS<\/jats:styled-content><jats:sup>(c)<\/jats:sup>, and all statistic inference comparisons were made using non\u2010parametric tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the first 15\u00a0days, children used a new regular toothbrush and <jats:styled-content style=\"fixed-case\">aPI<\/jats:styled-content>\u2010C (teeth adjacent to the cleft) was recorded. The Cleft Toothbrush, used by all children from day 15 to day 30, showed high efficacy in removing dental plaque in the cleft area, evidenced by significantly lower <jats:styled-content style=\"fixed-case\">aPI<\/jats:styled-content>\u2010C values, compared to those observed with the regular toothbrush (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). When given free option of brushing technique, from day 30 to day 60, most of the children (38 out of 45) chose the Cleft Toothbrush.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Cleft Toothbrush showed high efficacy in removing dental plaque in the cleft area, and presented high level of acceptance by parents and children, compared to a regular toothbrush. This is expected to improve the health status of the local adjacent tissues, a requirement for their rehabilitation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.12447","type":"journal-article","created":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T15:05:24Z","timestamp":1542121524000},"page":"213-220","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Oral hygiene of children with cleft lip and palate: Efficacy of the cleft toothbrush \u2010 A designed add\u2010on to regular toothbrushes"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7640-6993","authenticated-orcid":false,"given":"Rita","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Faculty of Dentistry University of Porto  Porto Portugal"},{"name":"Department of Dental Sciences Faculty of Health Sciences University Fernando Pessoa  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9391-9574","authenticated-orcid":false,"given":"Maria Helena","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry University of Porto  Porto Portugal"},{"name":"LAQV\/REQUIMTE University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Bessa","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Lusiadas Hospital  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rowney","family":"Furfuro","sequence":"additional","affiliation":[{"name":"Compor Clinic  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5274-1615","authenticated-orcid":false,"given":"C\u00e1tia Carvalho","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Dental Sciences Faculty of Health Sciences University Fernando Pessoa  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4254-1879","authenticated-orcid":false,"given":"Joaquim","family":"Mendes","sequence":"additional","affiliation":[{"name":"Faculty of Engineering University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1774-1337","authenticated-orcid":false,"given":"Maria Concei\u00e7\u00e3o","family":"Manso","sequence":"additional","affiliation":[{"name":"LAQV\/REQUIMTE University of Porto  Porto Portugal"},{"name":"Department of Dental Sciences Faculty of Health Sciences Fernando Pessoa Energy, Environment and Health Research Unit (FP\u2010ENAS) University Fernando Pessoa  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,12]]},"reference":[{"unstructured":"W. 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