{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T20:32:50Z","timestamp":1791837170861,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T00:00:00Z","timestamp":1551225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior - Brasil","doi-asserted-by":"crossref","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2019,7]]},"abstract":"Background<\/jats:title>Molar incisor hypomineralization (MIH<\/jats:styled-content>) is associated with unfavourable dental conditions such as dental caries and may consequently impact oral health\u2010related quality of life (OHRQ<\/jats:styled-content>oL).<\/jats:p><\/jats:sec>Objective<\/jats:title>To assess the impact of MIH<\/jats:styled-content> on OHRQ<\/jats:styled-content>oL in children with early mixed dentition.<\/jats:p><\/jats:sec>Method<\/jats:title>A population\u2010based cross\u2010sectional study of 728 8\u2010year\u2010old children from the public school system in Curitiba, Brazil, was conducted. The Child Perception Questionnaire for 8\u2010 to 10\u2010year\u2010olds (CPQ<\/jats:styled-content>8\u201010<\/jats:sub>) was used to evaluate OHRQ<\/jats:styled-content>oL. MIH<\/jats:styled-content> was diagnosed according to the European Academy of Paediatric Dentistry (EAPD<\/jats:styled-content>) criteria. The assessments of MIH<\/jats:styled-content>, dental caries, and malocclusion were performed by four calibrated examiners (\u03ba<\/jats:italic>\u00a0\u2265\u00a00.80). Demographic and socioeconomic data (DSE<\/jats:styled-content>) were obtained from the children's parents\/caregivers using a structured questionnaire. The analysis of OHRQ<\/jats:styled-content>oL determinants was performed through a three\u2010level hierarchical approach: mesial (DSE<\/jats:styled-content>), intermediate (clinical conditions), and distal (child's oral self\u2010perception), using Poisson regression with robust variance (\u03b1<\/jats:italic>\u00a0=\u00a00.05).<\/jats:p><\/jats:sec>Results<\/jats:title>The prevalence of MIH<\/jats:styled-content> was 12.1% (95% CI<\/jats:styled-content>: 10\u201015). An association was found between MIH<\/jats:styled-content> and OHRQ<\/jats:styled-content>oL in the \u201coral symptoms\u201d domain of the CPQ<\/jats:styled-content>8\u201010<\/jats:sub> (PR<\/jats:styled-content>: 1.07, 95% CI<\/jats:styled-content>: 1.03\u20101.11, P\u00a0<\/jats:italic><\u00a0<\/jats:italic>0.001) after adjusting for other clinical variables and DSE<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Molar incisor hypomineralization was associated with a greater impact on OHRQ<\/jats:styled-content>oL in children's oral symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.12482","type":"journal-article","created":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T14:38:00Z","timestamp":1550068680000},"page":"496-506","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":75,"title":["Impact of molar incisor hypomineralization on quality of life in children with early mixed dentition: A hierarchical approach"],"prefix":"10.1111","volume":"29","author":[{"given":"Paula Dresch","family":"Portella","sequence":"first","affiliation":[{"name":"Pediatric Dentistry Department of Stomatology Universidade Federal do Paran\u00e1 Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Leticia Vessoni","family":"Menoncin","sequence":"additional","affiliation":[{"name":"Pediatric Dentistry Department of Stomatology Universidade Federal do Paran\u00e1 Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9969-3721","authenticated-orcid":false,"given":"Juliana Feltrin","family":"de Souza","sequence":"additional","affiliation":[{"name":"Pediatric Dentistry Department of Stomatology Universidade Federal do Paran\u00e1 Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9178-0898","authenticated-orcid":false,"given":"Jos\u00e9 Vitor Nogara Borges","family":"de Menezes","sequence":"additional","affiliation":[{"name":"Pediatric Dentistry Department of Stomatology Universidade Federal do Paran\u00e1 Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5290-7905","authenticated-orcid":false,"given":"Fabian Calixto","family":"Fraiz","sequence":"additional","affiliation":[{"name":"Pediatric Dentistry Department of Stomatology Universidade Federal do Paran\u00e1 Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7380-8583","authenticated-orcid":false,"given":"Luciana Reichert da Silva","family":"Assun\u00e7\u00e3o","sequence":"additional","affiliation":[{"name":"Pediatric Dentistry Department of Stomatology Universidade Federal do Paran\u00e1 Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,27]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"110","article-title":"Judgment criteria for molar incisor hypomineralization (MIH) in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003","volume":"4","author":"Weerheijm KL","year":"2003","journal-title":"Eur J Paediatr Dent"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2008.00927.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016350902758607"},{"key":"e_1_2_9_5_1","first-page":"581","article-title":"The impact of molar\u2010incisor hypomineralisation on dental caries in permanent first molars: a prospective cohort study","volume":"15","author":"Costa Silva CM","year":"2017","journal-title":"Oral Health Prev Dent"},{"key":"e_1_2_9_6_1","first-page":"114","article-title":"Molar incisor hypomineralisation (MIH)","volume":"4","author":"Weerheijm KL","year":"2003","journal-title":"Eur J Paediatr Dent"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2007.00908.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12271"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107BOR-2016.vol30.0117"},{"issue":"1","key":"e_1_2_9_10_1","first-page":"247","article-title":"Oral health and quality of life","volume":"2","author":"Locker D","year":"2004","journal-title":"Oral Health Prev Dent"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2007.00418.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-83242011000600010"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-017-2079-1"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2011.01128.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03262716"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-10-6"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/26.1.224"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(00)00391-9"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-11-37"},{"key":"e_1_2_9_20_1","first-page":"512","article-title":"Questionnaire for measuring oral health\u2010related quality of life in eight\u2010 to ten\u2010year\u2010old children","volume":"26","author":"Jokovic A","year":"2004","journal-title":"Pediatr Dent"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6831-9-13"},{"key":"e_1_2_9_22_1","volume-title":"Oral Health Surveys: Basics Methods","author":"World Health Organization","year":"2013"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00056-007-1606-0"},{"key":"e_1_2_9_24_1","first-page":"38","article-title":"Oral health\u2010related quality of life in Colombian children with molar\u2010incisor hypomineralization","volume":"31","author":"Velandia LM","year":"2018","journal-title":"Acta Odontol Latinoam"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12233"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12002"},{"key":"e_1_2_9_27_1","first-page":"299","article-title":"Development of a questionnaire to measure perceptions of, and concerns derived from, dental fluorosis","volume":"21","author":"Mart\u00ednez\u2010Mier EA","year":"2004","journal-title":"Community Dent Health"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12323"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1159\/000336387"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.2319\/010912-20.1"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-009-9538-3"}],"container-title":["International Journal of Paediatric Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fipd.12482","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ipd.12482","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ipd.12482","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ipd.12482","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T23:20:00Z","timestamp":1694388000000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ipd.12482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,27]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1111\/ipd.12482"],"URL":"https:\/\/doi.org\/10.1111\/ipd.12482","archive":["Portico"],"relation":{},"ISSN":["0960-7439","1365-263X"],"issn-type":[{"value":"0960-7439","type":"print"},{"value":"1365-263X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,27]]},"assertion":[{"value":"2018-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}