{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:19:40Z","timestamp":1747185580316,"version":"3.40.5"},"reference-count":5,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T00:00:00Z","timestamp":1556150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Emanuel Syndrome (<jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>;<jats:styled-content style=\"fixed-case\"> OMIM<\/jats:styled-content># 609029) is a rare disorder caused by an unbalanced chromosomal translocation [supernumerary der(22)t(11,22)] and characterized by multiple congenital abnormalities. With limited published cases and low prevalence (1:110\u00a0000), detailed <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\u2010associated oro\u2010dental findings have not previously been reported. This is a case report of a 14\u2010year\u2010old boy with <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content> who presented with congenital cardiac, renal, auditory, musculoskeletal problems, and global developmental delay. The patient was managed with risperidone, melatonin, omeprazole, guanfacine, and oxcarbazepine. Anxiety\u2010associated self\u2010injurious behaviour was seen along with stereotypic hand movements. Consistent with previous reports, microcephaly and micrognathia were noted. Oro\u2010facial cleft or gross asymmetry, however, was not observed. Significant oro\u2010dental findings included delayed eruption of primary and permanent teeth, oligodontia (two erupted and five unerupted permanent teeth), and short\u2010root anomaly of central incisors. The patient demonstrated anxiety\u2010triggered bruxism with generalized attrition. This case report provides a comprehensive list of systemic <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content> findings along with oro\u2010dental manifestations, which have previously not been reported in detail.<\/jats:p>","DOI":"10.1111\/ipd.12502","type":"journal-article","created":{"date-parts":[[2019,4,13]],"date-time":"2019-04-13T13:13:00Z","timestamp":1555161180000},"page":"677-682","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Oral and dental findings in emanuel syndrome"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6500-0664","authenticated-orcid":false,"given":"Chaitanya P.","family":"Puranik","sequence":"first","affiliation":[{"name":"Division of Pediatric Dentistry Department of Craniofacial Sciences School of Dental Medicine University of Connecticut Health Center Farmington Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bina","family":"Katechia","sequence":"additional","affiliation":[{"name":"Division of Pediatric Dentistry Department of Craniofacial Sciences School of Dental Medicine University of Connecticut Health Center Farmington Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,25]]},"reference":[{"volume-title":"GeneReviews(\u00ae)","year":"1993","author":"Emanuel BS","key":"e_1_2_6_2_1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.12437"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32957"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-012-2288-4"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-014-1955-y"}],"container-title":["International Journal of Paediatric Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fipd.12502","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ipd.12502","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ipd.12502","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ipd.12502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T14:37:51Z","timestamp":1694270271000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ipd.12502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,25]]},"references-count":5,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1111\/ipd.12502"],"URL":"https:\/\/doi.org\/10.1111\/ipd.12502","archive":["Portico"],"relation":{},"ISSN":["0960-7439","1365-263X"],"issn-type":[{"type":"print","value":"0960-7439"},{"type":"electronic","value":"1365-263X"}],"subject":[],"published":{"date-parts":[[2019,4,25]]},"assertion":[{"value":"2019-01-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}