{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T23:38:50Z","timestamp":1788565130615,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T00:00:00Z","timestamp":1571875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the efficacy of treatment using a minimally invasive approach (selective removal of carious tissue, restoration and preventive strategies) in immature permanent molars with MIH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A total of 281 patients, aged 6\u20108\u00a0years, with carious lesions (ICDAS 5\u20106), severe MIH, and incomplete root formation (one tooth\/patient) were included. After clinical and radiographic examinations, selective carious tissue removal was performed, and the teeth received interim restoration for 6\u00a0months and were then restored with composite resin. Clinical and radiographic follow\u2010up was undertaken, 6, 12, 18, and 24\u00a0months. A protocol of preventive oral care measures was established and repeated at each follow\u2010up, including diet counselling, oral hygiene instruction, dental plaque control, and topical application of fluoride varnish containing CPP\u2010ACP. All clinical procedures and evaluations were done by a single operator.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Clinical and radiographic success was observed 24\u00a0months after treatment in 96.8% of the cases. Failures were due to enamel fracture at restoration margins, resulting in pulpitis and absence of apex closure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Selective removal of carious tissue, interim, and subsequently definitive restoration, combined with home and professional preventive measures, maintained marginal integrity of restorations in immature permanent molars with severe MIH, confirmed by pulp vitality and occurrence of apexogenesis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.12581","type":"journal-article","created":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T17:53:35Z","timestamp":1570557215000},"page":"4-10","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Minimally interventive restorative care of teeth with molar incisor hypomineralization and open apex\u2014A 24\u2010month longitudinal study"],"prefix":"10.1111","volume":"30","author":[{"given":"Patr\u00edcia","family":"Gat\u00f3n\u2010Hernand\u00e9z","sequence":"first","affiliation":[{"name":"School of Dentistry University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9sar Ruiz","family":"Serrano","sequence":"additional","affiliation":[{"name":"Instituto Catal\u00e3o da Sa\u00fade Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lea Assed Bezerra","family":"da Silva","sequence":"additional","affiliation":[{"name":"School of Dentistry of Ribeir\u00e3o Preto University of S\u00e3o Paulo Ribeir\u00e3o Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther Ruiz","family":"de Casta\u00f1eda","sequence":"additional","affiliation":[{"name":"M\u00ednima Interven\u00e7\u00e3o e Traumatismo Dental (MITD) Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel Assed Bezerra","family":"da Silva","sequence":"additional","affiliation":[{"name":"School of Dentistry of Ribeir\u00e3o Preto University of S\u00e3o Paulo Ribeir\u00e3o Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4876-6892","authenticated-orcid":false,"given":"Carolina Maschietto","family":"Pucinelli","sequence":"additional","affiliation":[{"name":"School of Dentistry of Ribeir\u00e3o Preto University of S\u00e3o Paulo Ribeir\u00e3o Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4570-0620","authenticated-orcid":false,"given":"David","family":"Manton","sequence":"additional","affiliation":[{"name":"Growth and Development Melbourne Dental School University of Melbourne Melbourne Vic. 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