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These adverse reactions are characterized by their severe involvement of the skin and the oral, gastrointestinal, genital, and conjunctival mucosa. The purposes of the study described herein were to perform a literature review of studies describing the clinical presentations and management of SJS patients with oral manifestations and to present a case report of a patient treated with dapsone gel. The research question for the literature review was the following: For patients with SJS, does adjunctive topical antibiotic treatment provide a better resolution for oral lesions than supportive care does? An online search of studies published from 2000 to 2019 was performed using the following databases: PubMed, BBO, LILACS, the Cochrane Library, and Ovid MEDLINE. Eight case reports were identified that met the inclusion criteria. Most of the articles included information about palliative treatments, such as supragingival cleaning and debridement, and the use of palliative oral rinses and gels, such as \u2018magic\u2019 mouthwash, chlorhexidine 0.12%, and lidocaine 2% gel. The case reported added an innovative treatment consisting of dapsone gel 5%.<\/jats:p>","DOI":"10.1111\/ipd.12615","type":"journal-article","created":{"date-parts":[[2020,1,10]],"date-time":"2020-01-10T22:58:04Z","timestamp":1578697084000},"page":"489-496","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Treatment for oral lesions in pediatric patients with Stevens\u2010Johnson's syndrome: A case report and literature review"],"prefix":"10.1111","volume":"30","author":[{"given":"Natalia","family":"Barea\u2010Jim\u00e9nez","sequence":"first","affiliation":[{"name":"Pediatric Dentistry Postdoctoral Program School of Dental Medicine University of Puerto Rico San Juan Puerto Rico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Calero","sequence":"additional","affiliation":[{"name":"Pediatric Dentistry Postdoctoral Program School of Dental Medicine University of Puerto Rico San Juan Puerto Rico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damaris","family":"Molina\u2010Negr\u00f3n","sequence":"additional","affiliation":[{"name":"Pediatric Dentistry Postdoctoral Program School of Dental Medicine University of Puerto Rico San Juan Puerto Rico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lydia M.","family":"L\u00f3pez Del\u2010Valle","sequence":"additional","affiliation":[{"name":"School of Dental Medicine University of Puerto Rico San Juan Puerto Rico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,24]]},"reference":[{"issue":"1","key":"e_1_2_12_2_1","first-page":"9","article-title":"Stevens\u2010Johnson syndrome: a review and report of two cases","volume":"39","author":"Gandhi RP","year":"2017","journal-title":"Pediatr Dent"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1586\/eci.11.66"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1995.01690170041005"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.4274\/tjh.2014.0470"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1993.01680220104023"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2004.00515.x"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7613.99344"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.27.1.r476g4640244t45g"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-013-0086-8"},{"issue":"3","key":"e_1_2_12_11_1","first-page":"576","article-title":"S\u00edndrome de Stevens\u2010Johnson: presentaci\u00f3n de un caso","volume":"15","author":"Qui\u00f1ones Hern\u00e1ndez J","year":"2011","journal-title":"Revista Archivo M\u00e9dico de Camag\u00fcey"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2018.02.016"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13719"}],"container-title":["International Journal of Paediatric Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fipd.12615","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ipd.12615","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ipd.12615","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ipd.12615","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T11:19:50Z","timestamp":1693999190000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ipd.12615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,24]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1111\/ipd.12615"],"URL":"https:\/\/doi.org\/10.1111\/ipd.12615","archive":["Portico"],"relation":{},"ISSN":["0960-7439","1365-263X"],"issn-type":[{"value":"0960-7439","type":"print"},{"value":"1365-263X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,24]]},"assertion":[{"value":"2019-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}