{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:20:30Z","timestamp":1791822030490,"version":"4.3.4"},"reference-count":46,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,9]],"date-time":"2020-03-09T00:00:00Z","timestamp":1583712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To summarize the clinical\/radiographic outcomes from the evidence of studies published since 1988 on different DPC agents applied on vital pulp\u2013exposed primary teeth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The following electronic databases were searched: PubMed, Embase, Cochrane Library, Dentistry and Oral Science Source, and Google Scholar. Inclusion criteria were randomized controlled trials (RCTs) published between January 1988 and December 2019, with at least 6\u00a0months of follow\u2010up, comparing the clinical and radiographic success rates of two or more DPC agents applied in primary teeth with cariously and non\u2010cariously exposed pulp.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Initial searches identified 83 potentially relevant studies on DPC in primary teeth. Sixty\u2010four of these studies were excluded, whereas 19 articles satisfied the inclusion criteria and were retrieved in full text for data extraction and a methodological quality assessment. Finally, 12 of these articles were included in the systematic review. Low and moderate risks of bias were observed. Overall, DPC clinical and radiographic success rates among the selected studies ranged between 53% and 100%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>For DPC in primary teeth, this systematic review found that diverse new biologically and compatible agents with promising success rates are currently available for paediatric dentistry practitioners. There is no evidence that justifies discarding the judicious use of DPC procedures in primary teeth.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.12633","type":"journal-article","created":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T16:07:46Z","timestamp":1582214866000},"page":"536-546","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Outcomes of direct pulp capping in vital primary teeth with cariously and non\u2010cariously exposed pulp: A systematic review"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9123-0300","authenticated-orcid":false,"given":"Arturo","family":"Garrocho\u2010Rangel","sequence":"first","affiliation":[{"name":"Paediatric Dentistry Postgraduate Program Faculty of Dentistry San Luis Potosi University San Luis Potosi SLP Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente","family":"Esparza\u2010Villalpando","sequence":"additional","affiliation":[{"name":"Basic Sciences Laboratory Faculty of Dentistry San Luis Potosi University San Luis Potosi SLP Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2314-8465","authenticated-orcid":false,"given":"Amaury","family":"Pozos\u2010Guillen","sequence":"additional","affiliation":[{"name":"Paediatric Dentistry Postgraduate Program Faculty of Dentistry San Luis Potosi University San Luis Potosi SLP Mexico"},{"name":"Basic Sciences Laboratory Faculty of Dentistry San Luis Potosi University San Luis Potosi SLP Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2006.00774.x"},{"key":"e_1_2_9_3_1","first-page":"CD003220","article-title":"Pulp treatment for extensive decay in primary teeth","volume":"5","author":"Sma\u00efl\u2010Faugeron V","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_4_1","first-page":"1348","article-title":"Direct pulp capping in treatment of reversible pulpitis in primary teeth \u2013 Clinical protocol","volume":"22","author":"Milcheva N","year":"2016","journal-title":"J Int Med Assoc Bulgaria (Oral & Dental Medicine)"},{"key":"e_1_2_9_5_1","first-page":"325","article-title":"Reference Manual. 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