{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:40:22Z","timestamp":1777725622546,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T00:00:00Z","timestamp":1604361600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The beneficial effect of the extraction of primary canines in the resolution of incisor irregularity and its side effects are controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To systematically review the effects of the extraction of primary canines in incisor irregularity and dental arch morphology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Controlled non\u2010randomized (non\u2010RCT) and randomized clinical trials (RCT) evaluating children treated with extraction of primary canines compared with those without intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 984 articles were found, of which two RCTs and one non\u2010RCT met the inclusion criteria. Both had a low RoB. A high level of evidence was observed through GRADE. A meta\u2010analysis showed the extraction of primary canines produced a significant decrease in incisor irregularity (95% CI: \u22123.56, \u22122.09\u00a0mm). This decrease, however, was associated with a reduction of arch length (95% CI: \u22121.58, \u22120.94\u00a0mm), intermolar width (95% CI: \u22120.61, \u22120.22\u00a0mm), and overjet (95% CI: \u2212075, \u2212018). A mild overbite increase was found (95% CI: 0.10, 0.76\u00a0mm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A high level of evidence showed that the extraction of primary canines improved incisor irregularity in the mixed dentition. Side effects included reduced arch length and intermolar width. A slight reduction in overjet and a mild increase in overbite were also observed. When they are not part of the treatment goal, these occlusal changes can be prevented by installing a lingual arch.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.12726","type":"journal-article","created":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T17:23:36Z","timestamp":1600449816000},"page":"583-597","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The effect of extraction of lower primary canines on the morphology of dental arch: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"31","author":[{"given":"Daybelis Gonz\u00e1lez","family":"Espinosa","sequence":"first","affiliation":[{"name":"Department of Orthodontics Dental School Federal University of Par\u00e1 Bel\u00e9m Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crislyne Mendes da Vera","family":"Cruz","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Dental School Federal 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