{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T18:06:03Z","timestamp":1783533963773,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T00:00:00Z","timestamp":1623715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hypomineralised second primary molar (HSPM) is a developmental enamel defect associated with dental caries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the impact of HSPM on oral health\u2013related quality of life (OHRQoL) in preschoolers through hierarchical analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>This population\u2010based cross\u2010sectional study assessed 834 5\u2010year\u2010old preschoolers, in Teresina, Piau\u00ed, Brazil, using sociodemographic questionnaires and Early Childhood Oral Health Impact Scale (ECOHIS). Dental examination was performed by two calibrated examiners (\u03ba\u00a0\u2265\u00a00.80) for the diagnosis of HSPM (EAPD), dental caries (dmft and pufa indices), and malocclusion (Foster and Hamilton criteria). Analysis of the determinants of OHRQoL was stratified at three levels (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Severe HSPM was associated with OHRQoL in bivariate analysis (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a0.05). In adjusted final multivariate analysis (model 1), the presence of dental caries with or without clinical consequences was associated with worse OHRQoL (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a0.05). In model 2, after the removal of dental caries, preschoolers with severe HSPM had greater probability of having a negative impact on OHRQoL in the child impact section (RR\u00a0=\u00a02.14; 95% CI\u00a0=\u00a01.26\u20103.65), family impact section (RR\u00a0=\u00a01.99; 95% CI\u00a0=\u00a01.16\u20103.42), and total score (RR\u00a0=\u00a02.09; 95% CI\u00a0=\u00a01.25\u20103.49) of the ECOHIS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Severe HSPM had a negative impact on the OHRQoL of preschoolers and their families, but the presence of dental caries neutralised this impact.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.12844","type":"journal-article","created":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T16:42:13Z","timestamp":1622565733000},"page":"194-203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Impact of hypomineralised second primary molar on preschoolers' oral health\u2013related quality of life\u2014A hierarchical approach"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9119-7045","authenticated-orcid":false,"given":"Renara Nat\u00e1lia","family":"Cerqueira Silva","sequence":"first","affiliation":[{"name":"Postgraduate Program in Dentistry Federal University of Piaui  Teresina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2977-6035","authenticated-orcid":false,"given":"Cacilda Castelo Branco","family":"Lima","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry Federal University of Piaui  Teresina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4849-8779","authenticated-orcid":false,"given":"Cristiane Baccin","family":"Bendo","sequence":"additional","affiliation":[{"name":"Department of Children and Adolescents Oral Health School of Dentistry Federal University of Minas Gerais  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano Rodrigues Silva","family":"Lima","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry Federal University of Piaui  Teresina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9044-9025","authenticated-orcid":false,"given":"Marcoeli Silva","family":"de Moura","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry Federal University of Piaui  Teresina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4112-1533","authenticated-orcid":false,"given":"L\u00facia de F\u00e1tima Almeida de Deus","family":"Moura","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry Federal University of Piaui  Teresina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7641-6331","authenticated-orcid":false,"given":"Marina de Deus Moura de","family":"Lima","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry Federal University of Piaui  Teresina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000135674"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512440450"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2012.01223.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091057"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-015-0179-7"},{"key":"e_1_2_9_7_1","first-page":"445","article-title":"Are hypomineralized primary molars and canines associated with molar\u2010incisor hypomineralization?","volume":"39","author":"da Silva Figueiredo S\u00e9 MJ","year":"2017","journal-title":"Pediatr Dent"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12584"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/adj.12567"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2017.03.006"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12583"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000500855"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000345213"},{"key":"e_1_2_9_14_1","volume-title":"Instituto Brasileiro de Geografia e Estat\u00edsticas. 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