{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T22:55:42Z","timestamp":1773960942127,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["123737\/2021\u20104"],"award-info":[{"award-number":["123737\/2021\u20104"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fluoride varnish (FV) is widely recommended for caries prevention in preschool children, despite its anticaries benefits being uncertain and modest. Dentists often report using clinical practice guidelines (CPGs) as a source of scientific information.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To identify and analyze recommendations for clinical practice on the use of FV for caries prevention in preschool children and to assess the methodological quality of the CPG on this topic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Two researchers independently used 12 search strategies and searched the first five pages of Google Search\u2122 and three guideline databases for recommendations freely available to health professionals on the use of FV for caries prevention in preschoolers. Then, they retrieved and recorded recommendations that met the eligibility criteria and extracted the data. A third researcher resolved disagreements. Each included CPG was appraised using the AGREE II instrument.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010nine documents were included. Recommendations varied according to age, patients' caries risk, and application frequency. Of the six CPGs, only one scored above 70% in the AGREE II overall assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Recommendations on the use of FV lacked scientific evidence, and CPGs were of poor quality. Application of FV is widely recommended despite recent evidence showing an uncertain, modest, and possibly not clinically relevant anticaries benefit. Dentists should be aware that it is necessary to critically appraise CPGs since they may be of poor quality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ipd.13074","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T23:15:51Z","timestamp":1682550951000},"page":"11-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Health professionals\u2019 recommendations on the use of fluoride varnish for caries prevention in preschool children"],"prefix":"10.1111","volume":"34","author":[{"given":"Fl\u00e1via Macedo","family":"Couto","sequence":"first","affiliation":[{"name":"Department of Community and Preventive Dentistry, Faculty of Dentistry Rio de Janeiro State University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda Santos de Oliveira","family":"de Sousa","sequence":"additional","affiliation":[{"name":"Department of Community and Preventive Dentistry, Faculty of Dentistry Rio de Janeiro State University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela Cristina","family":"Vicente","sequence":"additional","affiliation":[{"name":"Department of Community and Preventive Dentistry, Faculty of Dentistry Rio de Janeiro State University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Pereira de Faria","family":"Castro","sequence":"additional","affiliation":[{"name":"Department of Community and Preventive Dentistry, Faculty of Dentistry Rio de Janeiro State University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Nadanovsky","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Institute of Social Medicine Rio de Janeiro State University  Rio de Janeiro Brazil"},{"name":"Department of Epidemiology, National School of Public Health Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5688-4747","authenticated-orcid":false,"given":"Ana Paula Pires","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Department of Community and Preventive Dentistry, Faculty of Dentistry Rio de Janeiro State University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"Barja\u2010Fidalgo","sequence":"additional","affiliation":[{"name":"Department of Community and Preventive Dentistry, Faculty of Dentistry Rio de Janeiro State University  Rio de Janeiro Brazil"},{"name":"Department of Pediatric Dentistry and Orthodontics, School of Dentistry Universidade Federal do Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,7,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034520908533"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12490"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/idh.12494"},{"issue":"4","key":"e_1_2_10_5_1","article-title":"Topical fluoride (toothpastes, mouthrinses, gels or varnishes) for preventing dental caries in children and adolescents","volume":"2003","author":"Marinho VC","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000499639"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000348492"},{"key":"e_1_2_10_8_1","unstructured":"IAPD.Foundational articles and consensus recommendations: use of fluoride for caries prevention 2020. 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