{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T18:57:18Z","timestamp":1789498638424,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T00:00:00Z","timestamp":1722211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Premature loss of primary teeth presents a significant challenge in oral health, with conflicting views on using space maintainers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess mandibular arch space changes associated with premature lower primary molar (PM) loss with or without a space maintainer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A randomized clinical trial with children (6\u20139\u2009years old) with premature loss of a lower PM divided into two groups: control group (CG), without a space maintainer, and intervention group (IG), with a space maintainer. Dental casts were measured at baseline, 3 months, and 6\u2009months. Linear distance; intercanine width and length; and arch width, length, and perimeter were measured. ANOVA and <jats:italic>t<\/jats:italic>\u2010test were applied (<jats:italic>p<\/jats:italic>\u2009=\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010six patients (mean: 7.3\u2009years; standard deviation [SD]: 0.92) were included: 14 in CG and 12 in IG. CG had a greater space loss (\u22120.9\u2009mm; SD: 0.45) than IG (\u22120.4\u2009mm; SD: 0.61) at 3\u2009months (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). No difference between the groups was observed after 6\u2009months (<jats:italic>p<\/jats:italic>\u2009=\u2009.610). CG decreases space at 6\u2009months, especially with the first permanent molars without intercuspation (\u22122\u2009mm; SD: 0.71; <jats:italic>p<\/jats:italic>\u2009=\u2009.007).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Premature lower PM loss resulted in reduced arch space loss after 6\u2009months, regardless of a space maintainer use. CG showed more loss of space when the first permanent molars lacked intercuspal relationship.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.13239","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T06:48:16Z","timestamp":1722322096000},"page":"369-379","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessment of space changes in the lower dental arch after the premature unit loss of a primary molar: A randomized clinical trial"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1612-9234","authenticated-orcid":false,"given":"Bruna Borges","family":"de Souza","sequence":"first","affiliation":[{"name":"Department of Dentistry Federal University of Santa Catarina  Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Eduarda","family":"Evangelista","sequence":"additional","affiliation":[{"name":"Private Practice  Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana da Silva Pereira","family":"Andriani","sequence":"additional","affiliation":[{"name":"Private Practice  Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9936-7942","authenticated-orcid":false,"given":"Mariane","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Department of Dentistry Federal University of Santa Catarina  Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Miranda Santana","sequence":"additional","affiliation":[{"name":"Department of Dentistry Federal University of Santa Catarina  Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2835-9061","authenticated-orcid":false,"given":"Michele","family":"Bolan","sequence":"additional","affiliation":[{"name":"Department of Dentistry Federal University of Santa Catarina  Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2014.939709"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep21147"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12416"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-016-0247-7"},{"key":"e_1_2_12_6_1","first-page":"34","article-title":"Premature loss of primary teeth: part III, drifting patterns for different types of teeth after loss of adjoining teeth","volume":"46","author":"Hoffding J","year":"1979","journal-title":"J Dent Child"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2009.00990.x"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000430787"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjad006"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2008.00951.x"},{"issue":"10","key":"e_1_2_12_11_1","first-page":"753","article-title":"Guidelines on the use of space maintainers following premature loss of primary teeth","volume":"63","author":"Brothwell DJ","year":"1997","journal-title":"J Can Dent Assoc"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-023-03111-x"},{"key":"e_1_2_12_13_1","first-page":"14","article-title":"Space maintenance \u2013 or appropriate care?","volume":"94","author":"Northway W","year":"2012","journal-title":"J Mich Dent Assoc"},{"key":"e_1_2_12_14_1","first-page":"114","article-title":"Space management in the mixed dentition","volume":"42","author":"Norton LA","year":"1975","journal-title":"J Dent Child"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(71)90214-4"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2011.04.023"},{"issue":"4","key":"e_1_2_12_17_1","first-page":"295","article-title":"Effects of premature loss of deciduous molars","volume":"54","author":"Northway WM","year":"1984","journal-title":"Angle Orthod"},{"issue":"4","key":"e_1_2_12_18_1","first-page":"297","article-title":"Dental arch space changes following premature loss of primary first molars: a systematic review","volume":"30","author":"Tunison W","year":"2008","journal-title":"Pediatr Dent"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10266-016-0281-2"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.03.004"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.3758\/BRM.41.4.1149"},{"key":"e_1_2_12_22_1","unstructured":"DallalGE.Randomization.2008. Accessed April 14 2019.http:\/\/www.randomization.com"},{"key":"e_1_2_12_23_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2015"},{"issue":"6","key":"e_1_2_12_24_1","first-page":"e1","article-title":"Space loss following premature loss of primary second molars","volume":"63","author":"Alnahwi HH","year":"2015","journal-title":"Gen Dent"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12460"},{"issue":"2","key":"e_1_2_12_26_1","first-page":"117","article-title":"Loss of space and dental arch length after the loss of the lower first primary molar: a longitudinal study","volume":"22","author":"Cuoghi OA","year":"1998","journal-title":"J Clin Pediatr Dent"},{"issue":"4","key":"e_1_2_12_27_1","first-page":"311","article-title":"Space changes after premature loss of the mandibular primary first molar: a longitudinal study","volume":"22","author":"Lin Y\u2010TJ","year":"1998","journal-title":"J Clin Pediatr Dent"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-4388.26023"},{"key":"e_1_2_12_29_1","volume-title":"Development of the Human Dentition","author":"Van der Linden F","year":"2013"}],"container-title":["International Journal of Paediatric Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ipd.13239","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T05:28:20Z","timestamp":1738560500000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ipd.13239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,29]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1111\/ipd.13239"],"URL":"https:\/\/doi.org\/10.1111\/ipd.13239","archive":["Portico"],"relation":{},"ISSN":["0960-7439","1365-263X"],"issn-type":[{"value":"0960-7439","type":"print"},{"value":"1365-263X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,29]]},"assertion":[{"value":"2023-12-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}