{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T19:27:15Z","timestamp":1783798035106,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003758","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa e ao Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico do Maranh\u00e3o","doi-asserted-by":"publisher","award":["POS\u2010GRAD\u201002355\/21"],"award-info":[{"award-number":["POS\u2010GRAD\u201002355\/21"]}],"id":[{"id":"10.13039\/501100003758","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sickle cell anemia (SCA) is the most common hemoglobinopathy in Brazil and worldwide and is part of a group of chronic genetic diseases resulting from abnormalities in the structure of hemoglobin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the impact of oral health conditions on the quality of life (QoL) of children and adolescents with SCA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>This is a cross\u2010sectional study with a sample of 76 children and adolescents aged 8\u201314\u2009years. For inclusion, they were required to have a diagnosis of HbSS SCA in their medical records, without a pain crisis or any dental emergency in the last three months. The children and adolescents with SCA were from Hematology and Hemotherapy Center of Maranh\u00e3o. Demographic characteristics, socioeconomic status, oral hygiene, caries, malocclusion, and oral health\u2010related quality of life (OHRQoL) were assessed. OHRQoL was assessed using the Child Perceptions Questionnaire. Descriptive statistics, Student's <jats:italic>t<\/jats:italic> and Mann\u2212Whitney tests were performed (<jats:italic>\u03b1<\/jats:italic>\u2009=\u20095%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Brown race was the most prevalent for both age groups (8\u201310\u2009years\u201463.2% and 11\u201314\u2009years\u201457.9%). Predominant monthly family income for both age groups was below $106. Visible plaque and gingival bleeding were higher in children aged 8\u201310\u2009years. Dental caries significantly impacted the QoL of adolescents through the domain \u201coral symptom\u201d (<jats:italic>p<\/jats:italic>\u2009=\u2009.031). Malocclusion significantly impacted the QoL of adolescents (\u201ctotal score,\u201d <jats:italic>p<\/jats:italic>\u2009=\u2009.026; \u201csocial well\u2010being\u201d, <jats:italic>p<\/jats:italic>\u2009=\u2009.045).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Oral health impairment negatively affected the QoL of adolescents with SCA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.13266","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T04:34:51Z","timestamp":1725942891000},"page":"551-557","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of oral health conditions on the quality of life of children and adolescents with sickle cell anemia: A cross\u2010sectional study"],"prefix":"10.1111","volume":"35","author":[{"given":"Gra\u00e7a Maria Lopes","family":"Mattos","sequence":"first","affiliation":[{"name":"Post Graduated Program in Dentistry Ceuma University  S\u00e3o Lu\u00eds Maranh\u00e3o Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cayara Mattos","family":"Costa","sequence":"additional","affiliation":[{"name":"Post Graduated Program in Dentistry Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Maranh\u00e3o Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana Santos","family":"Malheiros","sequence":"additional","affiliation":[{"name":"Post Graduated Program in Dentistry Ceuma University  S\u00e3o Lu\u00eds Maranh\u00e3o Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam Batalha","family":"Maciel","sequence":"additional","affiliation":[{"name":"Post Graduated Program in Dentistry Ceuma University  S\u00e3o Lu\u00eds Maranh\u00e3o Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Bassi\u2010Dibai","sequence":"additional","affiliation":[{"name":"Post Graduated Program in Dentistry Ceuma University  S\u00e3o Lu\u00eds Maranh\u00e3o Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7116-1547","authenticated-orcid":false,"given":"Meire Coelho","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Post Graduated Program in Dentistry Ceuma University  S\u00e3o Lu\u00eds Maranh\u00e3o Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudys Rodolfo De Jesus","family":"Tavarez","sequence":"additional","affiliation":[{"name":"Post Graduated Program in Dentistry Ceuma University  S\u00e3o Lu\u00eds Maranh\u00e3o Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2016.153791"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2018.10"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107BOR-2015.vol29.0017"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.5581\/1516-8484.20130093"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/mph.0000000000001376"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/sjmms.sjmms_142_17"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10005-1301"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2007.00418.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12365"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-015-1681-3"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S151198"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjhh.2016.01.004"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-015-0052-4"},{"issue":"1","key":"e_1_2_12_15_1","first-page":"24","article-title":"The impact of sickle cell disease on oral health\u2010related quality of life","volume":"36","author":"Ralstrom E","year":"2014","journal-title":"Pediatr Dent"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.541782.AD"},{"key":"e_1_2_12_17_1","volume-title":"Oral Health Surveys: Basic Methods","author":"World Health Organization","year":"2013"},{"issue":"4","key":"e_1_2_12_18_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J","year":"1975","journal-title":"Int Dent J"},{"key":"e_1_2_12_19_1","volume-title":"DAI: the Dental Aesthetic Index","author":"Cons N","year":"1986"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1413-81232011001100013"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1413-81232011000800026"},{"key":"e_1_2_12_22_1","volume-title":"Atlas de Desenvolvimento Sustent\u00e1vel e Sa\u00fade. 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