{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T16:33:45Z","timestamp":1771518825216,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,9]],"date-time":"2025-03-09T00:00:00Z","timestamp":1741478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Moderate sedation is a behavior guidance technique in pediatric dentistry, and evaluating existing regimens can improve sedation outcomes and safety.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine if behavior at consult and sedation medication dosages is associated with sedation success and the patient's behavior using diazepam, meperidine, and hydroxyzine (DMH) regimen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A retrospective chart review of 324 patients who underwent 404 oral moderate sedations with (DMH) from April 2017 to June 2022. Sedations were graded as Successful or Unsuccessful and Positive (Frankl F3 or F4) or Negative (Frankl F1 or F2) behavior. Primary variables included Frankl behavior at consult and medication dosages. Logistic regression models were used to determine if these factors were associated with sedation success and behavior while adjusting for other patient and sedation characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>DMH yielded mostly successful sedations (89%) and Positive Behavior (Frankl F3 or F4) (72%). Lower Frankl scores at consult (OR: 2.3, <jats:italic>p<\/jats:italic>\u2009=\u20090.0140) were associated with increased odds of sedation failure. Increased age (OR: 0.8, <jats:italic>p<\/jats:italic>\u2009=\u20090.0047) was associated with decreased odds of failure. Meperidine dose demonstrated a significant association with improved sedation while controlling for age and behavior (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The (DMH) is an effective moderate sedation regimen. Patient selection is a significant factor in sedation success.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.13305","type":"journal-article","created":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T12:52:02Z","timestamp":1741611122000},"page":"906-912","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Diazepam, Meperidine, and Hydroxyzine as a Moderate Sedation Regimen in Pediatric Dentistry: A Retrospective Study"],"prefix":"10.1111","volume":"35","author":[{"given":"Taibah","family":"Albaker","sequence":"first","affiliation":[{"name":"Pediatric Dentistry Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Carrico","sequence":"additional","affiliation":[{"name":"School of Dentistry Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Hawkins","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiffany","family":"Williams","sequence":"additional","affiliation":[{"name":"Pediatric Dentistry Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,9]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"321","volume-title":"The Reference Manual of Pediatric Dentistry","author":"American Academy of Pediatric Dentistry","year":"2022"},{"issue":"5","key":"e_1_2_10_3_1","first-page":"346","article-title":"A Retrospective Study of Dosing Weight and Outcomes for One Pediatric Dental Sedation Regimen","volume":"40","author":"Olacke B.","year":"2018","journal-title":"Pediatric Dentistry"},{"issue":"4","key":"e_1_2_10_4_1","first-page":"302","article-title":"A Comparison of Sedation\u2010Related Events for Two Multiagent Oral Sedation Regimens in Pediatric Dental Patients","volume":"36","author":"McCormack L.","year":"2014","journal-title":"Pediatric Dentistry"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.2344\/0003-3006-62.3.91"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4625-46.2.11"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4628-39.5.481"},{"issue":"2","key":"e_1_2_10_8_1","first-page":"159","article-title":"A Survey of Members of the American Academy of Pediatric Dentistry on Their Use of Behavior Management Techniques","volume":"26","author":"Adair S. 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