{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:21:15Z","timestamp":1777861275847,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The association between light\u2010polymerised resin\u2010based fluoride\u2010releasing sealants and pit\u2010and\u2010fissure caries on primary molars is unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To investigate the efficacy of resin\u2010based fissure sealants in preventing caries on primary molars.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>In this retrospective study of patients attending a tertiary dental hospital for at least 30\u2009months, records of 106 children (275 teeth) were reviewed. Sealant placement on primary molars in the outpatient clinic (OPC) and under general anaesthesia (GA) was recorded, measuring caries incidence over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 275 teeth, 94 (34.2%) developed caries during this period. Among those carious teeth, 17 teeth (18.1%) were sealed compared to the 77 (81.9%) non\u2010sealed (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). In molars that developed caries, those sealed under GA were associated with longer caries\u2010free mean duration compared to the non\u2010sealed molars (3.07\u2009years compared with 2.32\u2009years, respectively,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Among teeth sealed in OPC, one tooth developed caries. An adjusted hazard ratio of 0.048 (95% CI: 0.025\u20130.090,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) demonstrated a 95.2% lower hazard of caries development in the sealant group compared to the non\u2010sealant group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Sealed primary molars are less likely to develop pit\u2010and\u2010fissure caries in OPC and GA, with a substantial long\u2010term protective effect observed in the GA\u2010treated group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ipd.70058","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T08:56:48Z","timestamp":1765789008000},"page":"396-404","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Investigation of the Efficacy of Resin\u2010Based Fissure Sealants in Preventing Caries on Primary Molars"],"prefix":"10.1111","volume":"36","author":[{"given":"Harleen","family":"Kumar","sequence":"first","affiliation":[{"name":"School of Dentistry, Faculty of Medicine and Health The University of Sydney  Sydney New South Wales Australia"},{"name":"Sydney Dental Hospital and Oral Health Services Sydney Local Health District  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5479-9650","authenticated-orcid":false,"given":"Shanika","family":"Nanayakkara","sequence":"additional","affiliation":[{"name":"School of Dentistry, Faculty of Medicine and Health The University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Halane","sequence":"additional","affiliation":[{"name":"School of Dentistry, Faculty of Medicine and Health The University of Sydney  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