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We tested whether parenteral fluid therapy improved weight loss from influenza infection. <jats:styled-content style=\"fixed-case\">BALB<\/jats:styled-content>\/c and C57<jats:styled-content style=\"fixed-case\">BL<\/jats:styled-content>\/6 mice were infected with <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">X<\/jats:styled-content>31 (<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>2) influenza and randomized to intraperitoneal fluid therapy. Blood glucose was also measured post\u2010viral infection on day 3 and 6 in <jats:styled-content style=\"fixed-case\">BALB<\/jats:styled-content>\/c mice and on day 6 in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>57<jats:styled-content style=\"fixed-case\">BL<\/jats:styled-content>\/6 mice. Parenteral fluids did not alter weight loss or the immunological response to infection, and glucose levels were not abnormal.<\/jats:p>","DOI":"10.1111\/irv.12066","type":"journal-article","created":{"date-parts":[[2012,12,24]],"date-time":"2012-12-24T15:38:14Z","timestamp":1356363494000},"page":"895-899","source":"Crossref","is-referenced-by-count":0,"title":["Parenteral fluids do not affect pulmonary immune responses to influenza or susceptibility to secondary bacterial pneumonia in mice"],"prefix":"10.1111","volume":"7","author":[{"given":"Robert D.","family":"Sanders","sequence":"first","affiliation":[{"name":"Department of Leukocyte Biology Imperial College London London UK"},{"name":"Department of Anaesthetics Intensive Care and Pain Medicine Imperial College London London UK"},{"name":"Wellcome Department of Imaging Neuroscience, University College London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Godlee","sequence":"additional","affiliation":[{"name":"Department of Leukocyte Biology Imperial College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Goulding","sequence":"additional","affiliation":[{"name":"Department of Leukocyte Biology Imperial College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daqing","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Anaesthetics Intensive Care and Pain Medicine Imperial College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mervyn","family":"Maze","sequence":"additional","affiliation":[{"name":"Department of Anesthesia &amp; Perioperative Care University of California San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy","family":"Hussell","sequence":"additional","affiliation":[{"name":"Department of Leukocyte Biology Imperial College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1637"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1521-4141(200109)31:9<2566::AID-IMMU2566>3.0.CO;2-L"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20030351"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181922bd3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc11154"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2009.01.005"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1765"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2006-0166OC"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir467"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V95.7.2312"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2011.04.006"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20070891"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc8916"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccc.2009.05.001"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc8012"}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Firv.12066","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.12066","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T07:41:52Z","timestamp":1696232512000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.12066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,24]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/irv.12066"],"URL":"https:\/\/doi.org\/10.1111\/irv.12066","archive":["Portico"],"relation":{},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"value":"1750-2640","type":"print"},{"value":"1750-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,24]]}}}