{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T02:05:58Z","timestamp":1768442758837,"version":"3.49.0"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,5,22]],"date-time":"2013-05-22T00:00:00Z","timestamp":1369180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"name":"Technologies Research and Development Program of the National Ministry of Science of China","award":["2009ZX10004-201"],"award-info":[{"award-number":["2009ZX10004-201"]}]},{"name":"Technologies Research and Development Program of the National Ministry of Science of China","award":["2009ZX10004-202"],"award-info":[{"award-number":["2009ZX10004-202"]}]},{"name":"Technologies Research and Development Program of the National Ministry of Science of China","award":["2012ZX10004201-003"],"award-info":[{"award-number":["2012ZX10004201-003"]}]},{"name":"Technologies Research and Development Program of the National Ministry of Science of China","award":["2012ZX10004-208"],"award-info":[{"award-number":["2012ZX10004-208"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Human adenovirus (<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>dV) type 14 had been infrequently associated with outbreaks of febrile respiratory illness (<jats:styled-content style=\"fixed-case\">FRI<\/jats:styled-content>) until the <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>dV\u201014p1 emerged in 2006 and rapidly spread in the United States. Here, we report an outbreak of <jats:styled-content style=\"fixed-case\">FRI<\/jats:styled-content> caused by HadV\u201014p1 that occurred in 2011 at a primary and middle school in China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>The basic information of the outbreak was recored; throat swabs were collected from 17 patients, polymerase chain reaction, A549 cell culture, and sequencing were used to identify the pathogen of the outbreak..<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Total of 43 students were infected in this outbreak. Boys were more than girls. We identified 11 <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>dV\u2010positive specimens and 6 <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>dV isolates. Genetic analysis showed that the complete hexon, fiber, and E1A sequences of isolates were nearly 100% identical with other <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>dV\u201014p1 sequences deposited in GenBank.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>HadV\u201014p1 has caused outbreaks of pneumonia and mortality among adults in the United States and Europe. It may cause similar conditions among Chinese adults due to poor hygiene and sanitation. It seems prudent for China to develop a national surveillance system to determine the etiology of severe respiratory diseases and deaths among adults and school\u2010aged children.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.12118","type":"journal-article","created":{"date-parts":[[2013,5,22]],"date-time":"2013-05-22T10:50:41Z","timestamp":1369219841000},"page":"1048-1054","source":"Crossref","is-referenced-by-count":37,"title":["Outbreak of febrile respiratory illness associated with human adenovirus type 14p1 in <scp>G<\/scp>ansu Province, <scp>C<\/scp>hina"],"prefix":"10.1111","volume":"7","author":[{"given":"Guohong","family":"Huang","sequence":"first","affiliation":[{"name":"Chinese Center for Disease Control and Prevention National Institute for Viral Disease Control and Prevention Beijing China"},{"name":"Xinjiang Medical University Urumqi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deshan","family":"Yu","sequence":"additional","affiliation":[{"name":"Gansu Center for Disease Control and Prevention Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Zhu","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention National Institute for Viral Disease Control and Prevention Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai","family":"Zhao","sequence":"additional","affiliation":[{"name":"Gansu Center for Disease Control and Prevention Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Wang","sequence":"additional","affiliation":[{"name":"Gansu Center for Disease Control and Prevention Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory C.","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Environmental and Global Health College of Public Health and Health Professions University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Meng","sequence":"additional","affiliation":[{"name":"Gansu Center for Disease Control and Prevention Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenbo","family":"Xu","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention National Institute for Viral Disease Control and Prevention Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,5,22]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1","volume-title":"Adenoviruses. 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