{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T15:18:54Z","timestamp":1789399134488,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T00:00:00Z","timestamp":1454025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Global Emerging Infections Surveillance Program (GEIS)","award":["GEIS847705\u00b7821000\u00b725GB.E0018"],"award-info":[{"award-number":["GEIS847705\u00b7821000\u00b725GB.E0018"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Acute respiratory infections (<jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content>s) are a major cause of morbidity and mortality worldwide. Influenza typically contributes substantially to the burden of <jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content>, but only limited data are available on influenza activity and seasonality in Jordan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Syndromic case definitions were used to identify individuals with severe acute respiratory infections (<jats:styled-content style=\"fixed-case\">SARI<\/jats:styled-content>) admitted to four sentinel hospitals in Jordan. Demographic and clinical data were collected. Nasopharyngeal and oropharyngeal swabs were tested for influenza using real\u2010time reverse transcription polymerase chain reaction and typed as influenza A or B, with influenza A further subtyped.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From January 2008\u2013February 2014, 2891 <jats:styled-content style=\"fixed-case\">SARI<\/jats:styled-content> cases were tested for influenza, and 257 (9%) were positive. While 73% of all <jats:styled-content style=\"fixed-case\">SARI<\/jats:styled-content> cases were under 5\u00a0years of age, only 57% of influenza\u2010positive cases were under 5\u00a0years of age. Eight (3%) influenza\u2010positive cases died. An annual seasonal pattern of influenza activity was observed. The proportion of influenza\u2010positive cases peaked during November\u2013January (14\u201342%) in the non\u2010pandemic years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Influenza is associated with substantial morbidity and mortality in Jordan. The seasonal pattern of influenza aligns with known Northern Hemisphere seasonality. Further characterization of the clinical and financial burden of influenza in Jordan will be critical in supporting decisions regarding disease control activities.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.12354","type":"journal-article","created":{"date-parts":[[2015,10,27]],"date-time":"2015-10-27T14:53:21Z","timestamp":1445957601000},"page":"91-97","source":"Crossref","is-referenced-by-count":23,"title":["Influenza hospitalization epidemiology from a severe acute respiratory infection surveillance system in <scp>J<\/scp>ordan, <scp>J<\/scp>anuary 2008\u2013<scp>F<\/scp>ebruary 2014"],"prefix":"10.1111","volume":"10","author":[{"given":"Mohammad","family":"Al\u2010Abdallat","sequence":"first","affiliation":[{"name":"Ministry of Health Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Dawson","sequence":"additional","affiliation":[{"name":"Global Disease Detection Center, U.S. Centers for Disease Control and Prevention Cairo Egypt"},{"name":"U.S. Naval Medical Research Unit No. 3 Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aktham Jeries","family":"Haddadin","sequence":"additional","affiliation":[{"name":"Ministry of Health Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waleed","family":"El\u2010Shoubary","sequence":"additional","affiliation":[{"name":"Global Disease Detection Center, U.S. Centers for Disease Control and Prevention Cairo Egypt"},{"name":"U.S. Naval Medical Research Unit No. 3 Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Dueger","sequence":"additional","affiliation":[{"name":"Global Disease Detection Center, U.S. Centers for Disease Control and Prevention Cairo Egypt"},{"name":"U.S. Naval Medical Research Unit No. 3 Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarek","family":"Al\u2010Sanouri","sequence":"additional","affiliation":[{"name":"Ministry of Health Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayar M.","family":"Said","sequence":"additional","affiliation":[{"name":"Global Disease Detection Center, U.S. Centers for Disease Control and Prevention Cairo Egypt"},{"name":"U.S. Naval Medical Research Unit No. 3 Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maha","family":"Talaat","sequence":"additional","affiliation":[{"name":"Global Disease Detection Center, U.S. Centers for Disease Control and Prevention Cairo Egypt"},{"name":"U.S. Naval Medical Research Unit No. 3 Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,29]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"World Health Organization.The world health report 2002 \u2013 Reducing risks promoting healthy life. 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