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Virus\u2010specific associations between seropositivity and occupational pig exposure were examined using multivariable regression models adjusted for vaccination. Pigs on the same farms were also tested for seropositivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010two percent of pigs were seropositive to A(H1N1)pdm09. Pig industry workers showed evidence of increased odds of A(H1N1)pdm09 seropositivity compared to the comparison group, albeit with wide confidence intervals (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>s), adjusted odds ratio after accounting for possible cross\u2010reactivity with other swine A(H1) viruses (aOR) 25\u00b73, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> (1\u00b74\u2013536\u00b73), <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7028.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results indicate that A(H1N1)pdm09 virus was common in <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> pigs during the pandemic and subsequent period of human A(H1N1)pdm09 circulation, and occupational exposure to pigs was a risk factor for human infection. Influenza immunisation of pig industry workers may reduce transmission and the potential for virus reassortment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.12364","type":"journal-article","created":{"date-parts":[[2015,11,27]],"date-time":"2015-11-27T07:32:43Z","timestamp":1448609563000},"page":"291-300","source":"Crossref","is-referenced-by-count":19,"title":["Increased risk of A(H1N1)pdm09 influenza infection in <scp>UK<\/scp> pig industry workers compared to a general population cohort"],"prefix":"10.1111","volume":"10","author":[{"given":"Ellen","family":"Fragaszy","sequence":"first","affiliation":[{"name":"Department of Infectious Disease Informatics Farr Institute of Health Informatics Research University College London London UK"},{"name":"Department of Infectious Disease Epidemiology London School of Hygiene and Tropical Medicine London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Ishola","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Informatics Farr Institute of Health Informatics Research University College London London UK"},{"name":"Immunisation Department Public Health England London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian H.","family":"Brown","sequence":"additional","affiliation":[{"name":"Animal and Plant Health Agency (formerly Animal Health and Veterinary Laboratories Agency) Weybridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Enstone","sequence":"additional","affiliation":[{"name":"Health Protection and Influenza Research Group Division of Epidemiology and Public Health University of Nottingham Nottingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan S.","family":"Nguyen\u2010Van\u2010Tam","sequence":"additional","affiliation":[{"name":"Health Protection and Influenza Research Group Division of Epidemiology and Public Health University of Nottingham Nottingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Simons","sequence":"additional","affiliation":[{"name":"Animal and Plant Health Agency (formerly Animal Health and Veterinary Laboratories Agency) Weybridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander W.","family":"Tucker","sequence":"additional","affiliation":[{"name":"Disease Dynamics Unit Department of Veterinary Medicine University of Cambridge Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Wieland","sequence":"additional","affiliation":[{"name":"Royal Veterinary College North Mymms UK"},{"name":"ILRI: International Livestock Research Institute Addis Ababa Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanna M.","family":"Williamson","sequence":"additional","affiliation":[{"name":"Animal and Plant Health Agency (formerly Animal Health and Veterinary Laboratories Agency) Weybridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew C.","family":"Hayward","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Informatics Farr Institute of Health Informatics Research University College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the Flu Watch Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James L. 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