{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:19:02Z","timestamp":1790756342725,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T00:00:00Z","timestamp":1471478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["71260"],"award-info":[{"award-number":["71260"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["127088"],"award-info":[{"award-number":["127088"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HHSN2722009000031"],"award-info":[{"award-number":["HHSN2722009000031"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HHSN27200002"],"award-info":[{"award-number":["HHSN27200002"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["HHSN261200800001E"],"award-info":[{"award-number":["HHSN261200800001E"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Respiratory syncytial virus (RSV) is a leading etiological agent of acute respiratory tract infections and hospitalizations in children. However, little information is available regarding RSV infections in Latin American countries, particularly among adult patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the epidemiology of RSV infection and to analyze the factors associated with severe infections in children and adults in Mexico.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients \u22651\u00a0month old, who presented with an influenza\u2010like illness (ILI) to six hospitals in Mexico, were eligible for participation in the study. Multiplex reverse\u2010transcriptase polymerase chain reaction identified viral pathogens in nasal swabs from 5629 episodes of ILI. Patients in whom RSV was detected were included in this report.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Respiratory syncytial virus was detected in 399 children and 171 adults. RSV A was detected in 413 cases and RSV B in 163, including six patients who had coinfection with both subtypes; 414 (72.6%) patients required hospital admission, including 96 (16.8%) patients that required admission to the intensive care unit. Coinfection with one or more respiratory pathogens other than RSV was detected in 159 cases. Young age (in children) and older age (in adults) as well as the presence of some underlying conditions were associated with more severe disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study confirms that RSV is an important respiratory pathogen in children in Mexico. In addition, a substantial number of cases in adults were also detected highlighting the relevance of this virus in all ages. It is important to identify subjects at high risk of complications who may benefit from current or future preventive interventions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.12414","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T07:44:06Z","timestamp":1469087046000},"page":"48-56","source":"Crossref","is-referenced-by-count":41,"title":["Epidemiology and clinical characteristics of respiratory syncytial virus infections among children and adults in Mexico"],"prefix":"10.1111","volume":"11","author":[{"given":"Ana E.","family":"Gami\u00f1o\u2010Arroyo","sequence":"first","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarbelio","family":"Moreno\u2010Espinosa","sequence":"additional","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Llamosas\u2010Gallardo","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Pediatr\u00eda  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana A.","family":"Ortiz\u2010Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Pediatr\u00eda  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Lourdes","family":"Guerrero","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arturo","family":"Galindo\u2010Fraga","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan F.","family":"Gal\u00e1n\u2010Herrera","sequence":"additional","affiliation":[{"name":"Mexico Emerging Infectious Diseases Clinical Research Network Coordinating Center  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"Prado\u2010Galbarro","sequence":"additional","affiliation":[{"name":"Agencia de Evaluaci\u00f3n de Tecnolog\u00edas Sanitarias Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Beigel","sequence":"additional","affiliation":[{"name":"Leidos Biomedical, Frederick, MD, in support of the National Institutes of Allergy and Infectious Diseases, National Institutes of Health  Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo M.","family":"Ruiz\u2010Palacios","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel E.","family":"Noyola","sequence":"additional","affiliation":[{"name":"Universidad Aut\u00f3noma de San Luis Potos\u00ed  San Luis Potos\u00ed Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Mexico Emerging Infectious Diseases Clinical Research Network (La Red)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)80040-3"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3325\/cmj.2013.54.122"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/174.3.456"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis309"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1128\/CMR.12.2.298","article-title":"Respiratory syncytial virus infection: immune response, immunopathogenesis, and treatment","volume":"12","author":"Domachowske JB","year":"1999","journal-title":"Clin Microbiol Rev"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2013.01.006"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00200-11"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01625-07"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60206-1"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000053882.70365.c9"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.1775"},{"key":"e_1_2_9_13_1","unstructured":"World Health Organization.CDC protocol of realtime RTPCR for swine influenza A(H1N1).http:\/\/www.who.int\/csr\/resources\/publications\/swineflu\/CDCrealtimeRTPCRprotocol_20090428.pdf. Accessed 27 February 2016."},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0888"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12234"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit839"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1086\/314567"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2013.09.021"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.67.469"},{"key":"e_1_2_9_20_1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.arbr.2014.11.020","article-title":"Viral coinfection in childhood respiratory tract infections","volume":"51","author":"Mart\u00ednez\u2010Roig A","year":"2015","journal-title":"Arch Bronconeumol"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.139188"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12224"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.77.6.508"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1086\/342414"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0120098"}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Firv.12414","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Firv.12414","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.12414","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T00:16:50Z","timestamp":1696205810000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.12414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,18]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/irv.12414"],"URL":"https:\/\/doi.org\/10.1111\/irv.12414","archive":["Portico"],"relation":{},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"value":"1750-2640","type":"print"},{"value":"1750-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,18]]}}}