{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T07:34:41Z","timestamp":1773041681069,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,8,30]],"date-time":"2016-08-30T00:00:00Z","timestamp":1472515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000145","name":"Alberta Innovates - Health Solutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000145","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000146","name":"Alberta Innovates - Technology Futures","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000146","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Emergency department (<jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>) visit volumes can be especially high during the Christmas\u2013New Year holidays, a period occurring during the influenza season in Canada.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using daily data, we examined the relationship between <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> visits for the chief complaint \u201ccough\u201d (for Edmonton, Alberta residents) and laboratory detections for influenza A and respiratory syncytial virus (<jats:styled-content style=\"fixed-case\">RSV<\/jats:styled-content>) (for Edmonton and surrounding areas), lagged 0\u20135\u00a0days ahead, for non\u2010pandemic years (2004\u20132008 and 2010\u20132014) using multivariable linear regression adjusting for temporal variables. We defined these cough\u2010related visits as influenza\u2010like illness (<jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content>)\u2010related <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> visits and, for 2004\u20132014, compared Christmas\u2013New Year holiday (December 24\u2013January 3) and non\u2010holiday volumes during the influenza season (October\u2013April).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Adjusting for temporal variables, <jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content>\u2010related <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> visits were significantly associated with laboratory detections for influenza A and <jats:styled-content style=\"fixed-case\">RSV<\/jats:styled-content>. During non\u2010pandemic years, the highest peak in <jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content>\u2010related visit volumes always occurred during the holidays. The median number of holiday <jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content>\u2010related visits\/day (42.5) was almost twice the non\u2010holiday median (24) and was even higher in 2012\u20132013 (80) and 2013\u20132014 (86). Holiday <jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content>\u2010related <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> visit volumes\/100\u00a0000 population ranged from 56.0 (2010\u20132011) to 117.4 (2012\u20132013). In contrast, lower visit volumes occurred during the holidays of pandemic\u2010affected years (2008\u20132010).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>During non\u2010pandemic years, <jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content>\u2010related <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> visit volumes were associated with variations in detections for influenza A and <jats:styled-content style=\"fixed-case\">RSV<\/jats:styled-content> and always peaked during the Christmas\u2013New Year holidays. This predictability should be used to prepare for, and possibly prevent, this increase in healthcare use; however, interventions beyond disease prevention strategies are likely needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.12416","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T15:46:45Z","timestamp":1469116005000},"page":"33-40","source":"Crossref","is-referenced-by-count":13,"title":["Influenza\u2010like illness\u2010related emergency department visits: Christmas and New Year holiday peaks and relationships with laboratory\u2010confirmed respiratory virus detections, Edmonton, Alberta, 2004\u20132014"],"prefix":"10.1111","volume":"11","author":[{"given":"Leah J.","family":"Martin","sequence":"first","affiliation":[{"name":"School of Public Health University of Alberta  Edmonton AB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cindy","family":"Im","sequence":"additional","affiliation":[{"name":"School of Public Health University of Alberta  Edmonton AB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiru","family":"Dong","sequence":"additional","affiliation":[{"name":"School of Public Health University of Alberta  Edmonton AB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bonita E.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Alberta  Edmonton AB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Talbot","sequence":"additional","affiliation":[{"name":"Office of the Chief Medical Officer of Health Alberta Health  Edmonton AB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David P.","family":"Meurer","sequence":"additional","affiliation":[{"name":"Alberta Health Services  Edmonton AB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shamir N.","family":"Mukhi","sequence":"additional","affiliation":[{"name":"School of Public Health University of Alberta  Edmonton AB Canada"},{"name":"Canadian Network for Public Health Intelligence National Microbiology Laboratory  Winnipeg MB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.","family":"Drews","sequence":"additional","affiliation":[{"name":"Provincial Laboratory for Public Health (ProvLab) Alberta Alberta Health Services  Edmonton AB Canada"},{"name":"Department of Laboratory Medicine and Pathology University of Alberta  Edmonton AB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Yasui","sequence":"additional","affiliation":[{"name":"School of Public Health University of Alberta  Edmonton AB Canada"},{"name":"Department of Epidemiology and Cancer Control St. Jude Children's Research Hospital  Memphis TN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,8,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2007.tb01451.x"},{"key":"e_1_2_6_3_1","unstructured":"CBC News.Flu outbreak crowding Canadian emergency rooms: Early spread of H3N2 flu virus affecting thousands of people nationwide: CBC; January 3 2013.http:\/\/www.cbc.ca\/news\/canada\/montreal\/story\/2013\/01\/03\/canada-health-flu-season-influenza.html. 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