{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T14:31:23Z","timestamp":1789655483353,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,9,30]],"date-time":"2017-09-30T00:00:00Z","timestamp":1506729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acute Respiratory Infections (<jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content>) are a leading cause of childhood mortality and morbidity. Malawi has high childhood mortality but limited data on the prevalence of disease in the community.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study of children aged 0\u201059\u00a0months. Health passports were examined for <jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content> diagnoses in the preceding 12\u00a0months. Children were physically examined for malnutrition or current <jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>828 children participated. The annual prevalence of <jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content> was 32.6% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 29.3\u201036.0%). Having a sibling with <jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.44, <jats:italic>P\u00a0<\/jats:italic>=\u00a0.01), increasing household density (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 2.17, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.02) and acute malnutrition (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.69, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.01) were predictors of infection in the last year. The point prevalence of <jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content> was 8.3% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 6.8\u201010.4%). Risk factors for current <jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content> were acute\u2010on\u2010chronic malnutrition (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 3.06, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.02), increasing household density (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>1.19, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.05) and having a sibling with <jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 2.30, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study provides novel data on the high prevalence of <jats:styled-content style=\"fixed-case\">ARI<\/jats:styled-content> in Malawi. This baseline data can be used in the monitoring and planning of future interventions in this population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.12481","type":"journal-article","created":{"date-parts":[[2017,9,21]],"date-time":"2017-09-21T10:12:40Z","timestamp":1505988760000},"page":"489-496","source":"Crossref","is-referenced-by-count":10,"title":["The prevalence and risk factors for acute respiratory infections in children aged 0\u201059\u00a0months in rural Malawi: A cross\u2010sectional study"],"prefix":"10.1111","volume":"11","author":[{"given":"Miriam","family":"Cox","sequence":"first","affiliation":[{"name":"School of Clinical and Experimental Medicine College of Medicine and Dental Sciences University of Birmingham  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Rose","sequence":"additional","affiliation":[{"name":"School of Clinical and Experimental Medicine College of Medicine and Dental Sciences University of Birmingham  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khumbo","family":"Kalua","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology College of Medicine University of Malawi  Blantyre Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"de Wildt","sequence":"additional","affiliation":[{"name":"School of Clinical and Experimental Medicine College of Medicine and Dental Sciences University of Birmingham  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Bailey","sequence":"additional","affiliation":[{"name":"Department of Clinical Research London School of Hygiene and Tropical Medicine  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Hart","sequence":"additional","affiliation":[{"name":"Department of Clinical Research London School of Hygiene and Tropical Medicine  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60678-2"},{"key":"e_1_2_8_3_1","unstructured":"World Health Organization[internet].Factsheet: Pneumonia.2014.http:\/\/www.who.int\/mediacentre\/factsheets\/fs331\/en\/. 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