{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:26:07Z","timestamp":1740147967198,"version":"3.37.3"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T00:00:00Z","timestamp":1524096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Healthcare personnel (<jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content>) are frequently exposed to influenza and can be a source of transmission to patients and other workers, resulting in high\u2010cost outbreaks for healthcare institutions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To analyse the presentation of <jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content> with influenza\u2010like illness (<jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content>) and the differences between individuals with influenza confirmed by polymerase chain reaction (<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>) and those with a negative test. The secondary objective was to evaluate the duration of symptomatology and work absenteeism as well as the vaccination rate of <jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content> at a paediatric referral hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional, descriptive study was conducted at a paediatric referral hospital. Clinical and epidemiological data on <jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content> were collected between January and April 2016. Nasopharyngeal swab for influenza <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> was obtained from one in every three workers with <jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content>. Telephone follow\u2010up was conducted to document duration of symptoms, complications and absenteeism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 164 <jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content> episodes were evaluated in 162 <jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content>. A swab was obtained in 59 cases, and influenza was detected in 30 cases. The clinical picture of <jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content> with confirmed influenza was similar to that of <jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content> with a negative <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>. Arthralgia was more common in those with influenza (90% vs 58%), with a tendency towards statistical significance. No <jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content> required hospitalization, and 78.5% were absent from work at least 1\u00a0day.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Influenza causes significant morbidity and absenteeism among <jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content>. Influenza infection was confirmed in only half of <jats:styled-content style=\"fixed-case\">HP<\/jats:styled-content> with an <jats:styled-content style=\"fixed-case\">ILI<\/jats:styled-content> on whom a <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> was performed, suggesting that other respiratory viruses can cause a similar pattern.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.12553","type":"journal-article","created":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T15:52:36Z","timestamp":1520265156000},"page":"475-481","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Influenza\u2010like illness in healthcare personnel at a paediatric referral hospital: Clinical picture and impact of the disease"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0188-578X","authenticated-orcid":false,"given":"Almudena","family":"Laris Gonz\u00e1lez","sequence":"first","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f3nica","family":"Villa Guill\u00e9n","sequence":"additional","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Briceida","family":"L\u00f3pez Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana E.","family":"Gami\u00f1o Arroyo","sequence":"additional","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarbelio","family":"Moreno Espinosa","sequence":"additional","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5086-3363","authenticated-orcid":false,"given":"Rodolfo Norberto","family":"Jim\u00e9nez Ju\u00e1rez","sequence":"additional","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luis","family":"S\u00e1nchez Huerta","sequence":"additional","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"de la Rosa Zamboni","sequence":"additional","affiliation":[{"name":"Hospital Infantil de M\u00e9xico Federico G\u00f3mez  Ciudad de M\u00e9xico M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,4,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2013.11.009"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/588162"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/502321"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2016.03.024"},{"key":"e_1_2_5_6_1","unstructured":"European Centre for Disease Prevention and Control.Influenza case definitions.http:\/\/ecdc.europa.eu\/en\/healthtopics\/influenza\/surveillance\/Pages\/influenza_case_definitions.aspx. 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