{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:17:19Z","timestamp":1790137039410,"version":"4.0.1"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T00:00:00Z","timestamp":1573084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Hamman-Hoffman Scholarship in Epidemiology, Colorado School of Public Health","award":["NA. This a student scholarship ($3,500)."],"award-info":[{"award-number":["NA. This a student scholarship ($3,500)."]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>National estimates of influenza burden may not reflect state\u2010level influenza activity, and local surveillance may not capture the full burden of influenza.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>To provide state\u2010level information about influenza burden, we estimated excess pneumonia and influenza (P&amp;I) and respiratory and circulatory (R&amp;C) hospitalizations and deaths in Colorado from local hospital discharge records, death certificates, and influenza virus surveillance using negative binomial models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From July 2007 to June 2016, influenza was associated with an excess of 17\u00a0911 P&amp;I hospitalizations (95%CI: 15\u00a0227, 20\u00a0354), 30\u00a0811 R&amp;C hospitalizations (95%CI: 24\u00a0344, 37\u00a0176), 1,064 P&amp;I deaths (95%CI: 757, 1298), and 3828 R&amp;C deaths (95%CI: 2060, 5433). There was a large burden of influenza A(H1N1) among persons aged 0\u201064\u00a0years, with high median seasonal rates of excess hospitalization among persons aged 0\u20104\u00a0years. Persons aged \u226565\u00a0years experienced the largest numbers and highest median seasonal rates of excess hospitalization and death associated with influenza A (H3N2). The burden of influenza B was generally lower, with elevated median seasonal rates of excess hospitalization among persons aged 0\u20104\u00a0years and \u226565\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings complement existing influenza surveillance. Periodic state\u2010level estimates of influenza disease burden may be useful for setting state public health priorities and planning prevention and control initiatives.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.12700","type":"journal-article","created":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T05:49:56Z","timestamp":1573192196000},"page":"111-121","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["State\u2010level estimates of excess hospitalizations and deaths associated with influenza"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1742-514X","authenticated-orcid":false,"given":"Christopher A.","family":"Czaja","sequence":"first","affiliation":[{"name":"Colorado Department of Public Health and Environment Denver CO USA"},{"name":"Colorado School of Public Health Aurora CO USA"},{"name":"University of Colorado School of Medicine Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Miller","sequence":"additional","affiliation":[{"name":"Colorado School of Public Health Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Colborn","sequence":"additional","affiliation":[{"name":"Colorado School of Public Health Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myles G.","family":"Cockburn","sequence":"additional","affiliation":[{"name":"Colorado School of Public Health Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisha","family":"Alden","sequence":"additional","affiliation":[{"name":"Colorado Department of Public Health and Environment Denver CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel K.","family":"Herlihy","sequence":"additional","affiliation":[{"name":"Colorado Department of Public Health and Environment Denver CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A. F.","family":"Sim\u00f5es","sequence":"additional","affiliation":[{"name":"Colorado School of Public Health Aurora CO USA"},{"name":"University of Colorado School of Medicine Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2007.03.046"},{"issue":"33","key":"e_1_2_6_3_1","first-page":"1057","article-title":"Estimates of deaths associated with seasonal influenza \u2013\u2010 United States, 1976\u20132007","volume":"59","author":"Centers for Disease Control and Prevention","year":"2010","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis211"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2008.151944"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-2659.2009.00073.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix740"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix1144"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12096"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)33293-2"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwt235"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis415"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080481"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113903"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1086\/425315"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12515"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.02.042"},{"key":"e_1_2_6_18_1","unstructured":"United States Census Bureau.American Community Survey.https:\/\/www.census.gov\/programs-surveys\/acs\/. Accessed May 2 2017."},{"key":"e_1_2_6_19_1","unstructured":"Centers for Disease Control and Prevention.FluView.https:\/\/www.cdc.gov\/flu\/weekly\/ 2017."},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciq008"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511973420"},{"key":"e_1_2_6_22_1","unstructured":"Colorado Department of Public Health and Environment.Influenza (flu).https:\/\/www.colorado.gov\/pacific\/cdphe\/influenza. Accessed March 2019."},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118369"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix694"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0064198"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1086\/511989"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e31826c2dda"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12486"}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Firv.12700","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.12700","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/irv.12700","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.12700","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T15:31:54Z","timestamp":1694014314000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.12700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,7]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1111\/irv.12700"],"URL":"https:\/\/doi.org\/10.1111\/irv.12700","archive":["Portico"],"relation":{},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"value":"1750-2640","type":"print"},{"value":"1750-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,7]]},"assertion":[{"value":"2019-04-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}