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Specimens tested negative for influenza were then tested for RSV and other respiratory pathogens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 8436 influenza\u2010negative specimens tested during the five\u2010year period, 5.8% (95% confidence interval 5.3%\u20106.3%) were positive for RSV. The peak of RSV activity occurred around middle of the year. The age\u2010specific proportion of RSV detections showed a reverse J\u2010shaped pattern; RSV positivity was the highest in young children \u22642\u00a0years of age (10.9%), followed by those aged 3\u20105\u00a0years (6.4%) and persons aged \u226565\u00a0years (5.3%), while the nadir was observed in the age group of 15\u201024\u00a0years (1.2%). RSV type A was predominantly circulating in children \u22645\u00a0years of age from 2014 to 2015 and 2017, whereas in 2016, they were more affected by type B.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Respiratory syncytial virus was more frequently detected among the two age groups that have been recommended for influenza vaccination; persons \u226565\u00a0years of age and children 6\u00a0months to &lt;5\u00a0years of age. Characterisation of RSV activity in the community helps to better inform public health policies for effective prevention and control interventions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.12730","type":"journal-article","created":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T08:38:06Z","timestamp":1582533486000},"page":"412-419","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Characterisation of respiratory syncytial virus activity in children and adults presenting with acute respiratory illness at primary care clinics in Singapore, 2014\u20102018"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0036-255X","authenticated-orcid":false,"given":"Li Wei","family":"Ang","sequence":"first","affiliation":[{"name":"National Centre for Infectious Diseases Singapore City Singapore"},{"name":"Public Health Group Ministry of Health Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tze Minn","family":"Mak","sequence":"additional","affiliation":[{"name":"National Centre for Infectious Diseases Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Cui","sequence":"additional","affiliation":[{"name":"National Centre for Infectious Diseases Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yee Sin","family":"Leo","sequence":"additional","affiliation":[{"name":"National Centre for Infectious Diseases Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vernon Jian Ming","family":"Lee","sequence":"additional","affiliation":[{"name":"Public Health Group Ministry of Health Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond Tzer\u2010Pin","family":"Lin","sequence":"additional","affiliation":[{"name":"National Centre for Infectious Diseases Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60206-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30938-8"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23570"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40121-016-0123-0"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz059"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30310-4"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1086\/506350"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-008-0035-4"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181af61e9"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-12-32"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ065"},{"key":"e_1_2_6_13_1","unstructured":"World Health Organization.Research needs for the battle against respiratory viruses (BRaVe).https:\/\/www.who.int\/influenza\/patient_care\/clinical\/research_agenda\/en\/. 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