{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:34:04Z","timestamp":1762522444528,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,5,10]],"date-time":"2020-05-10T00:00:00Z","timestamp":1589068800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014101","name":"Novavax","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100014101","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We developed and evaluated a model to predict serious outcomes among 243 adults \u226560\u00a0years old with medically attended respiratory illness and laboratory\u2010confirmed respiratory syncytial virus (RSV); 47 patients had a serious outcome defined as hospital admission, emergency department (ED) visit, or pneumonia diagnosis. The model used logistic regression with penalized maximum likelihood estimation. The reduced penalized model included age \u2265\u00a075\u00a0years, \u22651 ED visit in prior year, crackles\/rales, tachypnea, wheezing, new\/increased sputum, and new\/increased dyspnea. The optimal score cutoff yielded sensitivity and specificity of 66.0% and 81.6%. This prediction model provided moderate utility for identifying older adults with elevated risk of complicated RSV illness.<\/jats:p>","DOI":"10.1111\/irv.12751","type":"journal-article","created":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T04:13:30Z","timestamp":1589170410000},"page":"479-482","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prediction of serious RSV\u2010related outcomes in older adults with outpatient RSV respiratory illness during 12 consecutive seasons"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7430-0570","authenticated-orcid":false,"given":"Burney A.","family":"Kieke","sequence":"first","affiliation":[{"name":"Marshfield Clinic Research Institute Marshfield Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7478-0415","authenticated-orcid":false,"given":"Edward A.","family":"Belongia","sequence":"additional","affiliation":[{"name":"Marshfield Clinic Research Institute Marshfield Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"McClure","sequence":"additional","affiliation":[{"name":"Marshfield Clinic Research Institute Marshfield Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek","family":"Shinde","sequence":"additional","affiliation":[{"name":"Novavax, Inc Gaithersburg Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix432"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-015-0258-9"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/187152612800100116"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25285"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofy316"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-3462-1"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19980430)17:8<909::AID-SIM753>3.0.CO;2-O"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2004.01.020"},{"volume-title":"Analyzing Receiver Operating Characteristic Curves with SAS","year":"2007","author":"Gonen M","key":"e_1_2_6_10_1"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwj063"}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Firv.12751","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.12751","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/irv.12751","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.12751","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T20:54:51Z","timestamp":1693860891000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.12751"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,10]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/irv.12751"],"URL":"https:\/\/doi.org\/10.1111\/irv.12751","archive":["Portico"],"relation":{},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"type":"print","value":"1750-2640"},{"type":"electronic","value":"1750-2659"}],"subject":[],"published":{"date-parts":[[2020,5,10]]},"assertion":[{"value":"2019-08-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}