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We tested 70 COVID\u201019 sera collected up to 85\u00a0days post\u2010symptom onset and 230 non\u2010COVID\u201019 sera, including 27 SARS sera from 2003. Although the average SARS\u2010CoV\u20102 S and N\u2010IgG titers were comparable, N\u2010responses were more variable among individuals. S\u2010 and N\u2010assay specificity tested with non\u2010COVID\u201019 sera were comparable at 97.5% and 97.0%, respectively. Therefore, S will make a better target due to its lower cross\u2010reactive potential and its' more consistent frequency of detection compared to N.<\/jats:p>","DOI":"10.1111\/irv.12798","type":"journal-article","created":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T14:45:36Z","timestamp":1598453136000},"page":"7-12","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Human post\u2010infection serological response to the spike and nucleocapsid proteins of SARS\u2010CoV\u20102"],"prefix":"10.1111","volume":"15","author":[{"given":"Cheng","family":"Xiao","sequence":"first","affiliation":[{"name":"Guangzhou Medical University Guangzhou China"},{"name":"State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory Disease Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiman","family":"Ling","sequence":"additional","affiliation":[{"name":"Guangzhou 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