{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T22:54:29Z","timestamp":1790463269610,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T00:00:00Z","timestamp":1607126400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["RFA\u2010GH\u201013\u201000102CONT14"],"award-info":[{"award-number":["RFA\u2010GH\u201013\u201000102CONT14"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We assessed EV\u2010D68 epidemiology and phylogenetics among children aged \u22649\u00a0years hospitalized with severe acute respiratory illnesses at five sites in Panama and El Salvador during 2012\u20102013. Respiratory specimens positive for enterovirus or rhinovirus were tested by real\u2010time RT\u2010PCR for EV\u2010D68, and partial VP1 gene sequences were determined. Of 715 enrolled children, 17 from sites in both countries were EV\u2010D68\u2010positive and commonly had a history of asthma or wheezing. Phylogenetically, 15 of 16 sequences fell into Clade B1, and one into Clade A2. The Central American EV\u2010D68s were closely related genetically to contemporaneous strains from North America, South America, and the Caribbean.<\/jats:p>","DOI":"10.1111\/irv.12815","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T22:39:48Z","timestamp":1607207988000},"page":"181-187","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Enterovirus D68 infection among hospitalized children with severe acute respiratory illness in El Salvador and Panama, 2012\u20102013"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4949-2232","authenticated-orcid":false,"given":"Holly M.","family":"Biggs","sequence":"first","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Allan","family":"Nix","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Rogers","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3779-3449","authenticated-orcid":false,"given":"Wilfrido","family":"Clara","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge H.","family":"Jara","sequence":"additional","affiliation":[{"name":"Centro de Estudios en Salud Universidad del Valle de Guatemala  Guatemala City Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalba","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Gorgas Memorial Institute for Health Studies  Panama City Panama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathia","family":"Luciani","sequence":"additional","affiliation":[{"name":"Hospital De Especialidades Pedi\u00e1tricas Omar Torrijos  Panama City Panama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yarisa Sujey","family":"Brizuela","sequence":"additional","affiliation":[{"name":"Hospital San Juan De Dios  San Miguel El Salvador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dora","family":"Estripeaut","sequence":"additional","affiliation":[{"name":"Hospital Del Ni\u00f1o  Panama City Panama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Miguel","family":"Castillo","sequence":"additional","affiliation":[{"name":"Hospital San Juan De Dios  Santa Ana El Salvador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tirza","family":"De Leon","sequence":"additional","affiliation":[{"name":"Hospital Materno Infantil Jos\u00e9 Domingo De Obald\u00eda  David Panama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Corro","sequence":"additional","affiliation":[{"name":"Hospital De Especialidades Pedi\u00e1tricas Omar Torrijos  Panama City Panama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ofelina","family":"Vergara","sequence":"additional","affiliation":[{"name":"Hospital Del Ni\u00f1o  Panama City Panama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Rauda","sequence":"additional","affiliation":[{"name":"Hospital San Juan De Dios  Santa Ana El Salvador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evens G.","family":"Chong","sequence":"additional","affiliation":[{"name":"Hospital Materno Infantil Jos\u00e9 Domingo De Obald\u00eda  David Panama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John T.","family":"Watson","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Azziz\u2010Baumgartner","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan I.","family":"Gerber","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suxiang","family":"Tong","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatimah S.","family":"Dawood","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(15)00335-5"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6718a2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2015.20.43.30047"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-10-305"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/emi.2015.66"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12384"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2104.141766"},{"key":"e_1_2_10_9_1","first-page":"e11","article-title":"First reported enterovirus D68 infection in pediatric patients from the Caribbean region: evidence of spread from the U.S. outbreak","volume":"41","author":"Nathaniel S","year":"2017","journal-title":"Rev Panam Salud Publica"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-01349-4"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6812a1"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2503.170897"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2016.07.007"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix148"},{"key":"e_1_2_10_15_1","unstructured":"Enterovirus D68 2014 Real\u2010Time RT\u2010PCR Assay.2015. 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