{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T11:29:50Z","timestamp":1778758190342,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T00:00:00Z","timestamp":1640563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013017","name":"Vanderbilt University Medical Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013017","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We assessed the prevalence and incidence of SARS\u2010CoV\u20102 infections in a prospective study of households in Lima, Peru.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Households with a child, a young adult 18\u201350\u2009years, and an adult age &gt;50\u2009years in peri\u2010urban Lima were followed with twice\u2010a\u2010week household visits during a 2\u2010month period. Nasal swabs and saliva specimens were collected twice weekly, and nasopharyngeal swabs were collected weekly from each participant, regardless of symptoms. Laboratory\u2010confirmed SARS\u2010CoV\u20102 infection was defined by two RT\u2010PCR tests from any of the collected specimens within a week. Blood samples collected at enrollment and end of follow\u2010up were tested with rapid serological tests. We calculated the prevalence and incidence of laboratory\u2010confirmed SARS\u2010CoV\u20102 infections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We enrolled 132 participants from 44 households: 44 children, 44 young adults, and 44 older adults. A total of 13 SARS\u2010CoV\u20102 infections were detected in eight households, for an overall period prevalence of 9.85% (95% confidence interval [CI]: 5.35\u201316.25). Most (61.54%) infections were symptomatic. Eight of 11 (72.73%) SARS\u2010CoV\u20102 detections corresponded to the Lambda variant. During 218.79 person\u2010months at risk of follow\u2010up, there were six new SARS\u2010CoV\u20102 infections detected (2.74 per 100 person\u2010month, 95% CI: 1.25\u20136.04). At enrollment, 59 of 128 participants tested had positive SARS\u2010CoV\u20102 IgG serology (46.09%, 95% CI: 37.25\u201355.12). Five of six new infections occurred among participants with negative baseline serology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We demonstrated high incidence of SARS\u2010CoV\u20102 infections in households, especially among subjects without evidence of prior infection, most of them not detected by the Ministry of Health system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.12952","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T01:12:28Z","timestamp":1640653948000},"page":"386-394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["SARS\u2010CoV\u20102 infections in households in a peri\u2010urban community of Lima, Peru: A prospective cohort study"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6994-7425","authenticated-orcid":false,"given":"Claudio F.","family":"Lanata","sequence":"first","affiliation":[{"name":"Instituto de Investigaci\u00f3n Nutricional  Lima Peru"},{"name":"Vanderbilt University  Nashville Tennessee USA"},{"name":"London School of Hygiene and Tropical Medicine  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3766-4364","authenticated-orcid":false,"given":"Ana I.","family":"Gil","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Nutricional  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6887-2356","authenticated-orcid":false,"given":"Lucie","family":"Ecker","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Nutricional  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2136-1759","authenticated-orcid":false,"given":"Rubelio","family":"Cornejo","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Nutricional  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3041-2770","authenticated-orcid":false,"given":"Stefano","family":"Rios","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Nutricional  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8002-3314","authenticated-orcid":false,"given":"Mayra","family":"Ochoa","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Nutricional  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5534-3658","authenticated-orcid":false,"given":"Bia","family":"Pe\u00f1a","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Nutricional  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1883-3572","authenticated-orcid":false,"given":"Omar","family":"Flores","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Nutricional  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4301-7235","authenticated-orcid":false,"given":"Leigh M.","family":"Howard","sequence":"additional","affiliation":[{"name":"Vanderbilt University and Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2329-7797","authenticated-orcid":false,"given":"Carlos G.","family":"Grijalva","sequence":"additional","affiliation":[{"name":"Vanderbilt University and Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6944e1"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-021-06443-7"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7037e1"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1825"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m4529"},{"issue":"6","key":"e_1_2_10_7_1","first-page":"736","article-title":"Viral shedding and transmission potential of asymptomatic 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Fallecidos hospitalizados y vacunados por COVID\u201019 SINADEF: Certificado Defunciones Vacunas Covid\u201019.https:\/\/www.datosabiertos.gob.pe\/search\/field_topic\/covid-19-917?sort_by=changed"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27261"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2034545"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.100801"}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.12952","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/irv.12952","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.12952","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T06:34:32Z","timestamp":1692945272000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.12952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,27]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1111\/irv.12952"],"URL":"https:\/\/doi.org\/10.1111\/irv.12952","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/IRV.12952\/v1\/decision1","asserted-by":"object"}]},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"value":"1750-2640","type":"print"},{"value":"1750-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,27]]},"assertion":[{"value":"2021-12-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}