{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T21:11:27Z","timestamp":1790370687240,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T00:00:00Z","timestamp":1644969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Few long\u2010term reports have been published on the epidemiology of respiratory viruses despite their frequent involvement in extremely common infections. The aim here was to determine the frequency and distribution of respiratory viruses in a temperate climate area (Barcelona, Spain) throughout a 24\u2010year period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We collected data on all respiratory viruses detected from 1997 to 2020 in our institution. Clinical specimens were analyzed mainly by conventional techniques, and molecular techniques were also used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 59,579 specimens analyzed, 21,382 (35.9%) were positive for at least one virus. The number of positive samples during cold months was significantly higher than in warm months. Respiratory virus infections were detected in patients of all ages, above all in children under 3\u2009years of age, who were most frequently infected with the respiratory syncytial virus, whereas Influenza A virus predominated in the other groups, especially in adults. A clear demographic and seasonal pattern was established for some viruses. Circulation of other respiratory viruses during the FLUAV H1N1pdm09 and SARS\u2010CoV\u20102 pandemics was observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This long\u2010term study provides new knowledge about the prevalence of respiratory viruses in a Mediterranean region. Throughout the study period, the frequency of some viruses remained constant, whereas others varied with the year. A clear demographic and seasonal pattern was established for some viruses. Patients suffering from severe respiratory infections should be examined for a range of respiratory viruses regardless of gender, age, or season.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.12972","type":"journal-article","created":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T04:07:20Z","timestamp":1644984440000},"page":"756-766","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Prevalence and seasonality of viral respiratory infections in a temperate climate region: A 24\u2010year study (1997\u20132020)"],"prefix":"10.1111","volume":"16","author":[{"given":"Laura","family":"Garc\u00eda\u2010Arroyo","sequence":"first","affiliation":[{"name":"Microbiology Department. Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona (UAB) Sant Pau Biomedical Research Institute (IIB Sant Pau)  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00faria","family":"Prim","sequence":"additional","affiliation":[{"name":"Microbiology Department. Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona (UAB) Sant Pau Biomedical Research Institute (IIB Sant Pau)  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marga","family":"Del Cuerpo","sequence":"additional","affiliation":[{"name":"Microbiology Department. Hospital de la Santa Creu i Sant Pau, Universitat Aut\u00f2noma de Barcelona (UAB) Sant Pau Biomedical Research Institute (IIB Sant Pau)  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Mar\u00edn","sequence":"additional","affiliation":[{"name":"Microbiology Department. 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