{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T16:10:55Z","timestamp":1778256655081,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,6,26]],"date-time":"2022-06-26T00:00:00Z","timestamp":1656201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004423","name":"World Health Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004423","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Health care workers (HCWs) represent a vulnerable population during epidemic periods. Our cohort study aimed to estimate the risk of infection and associated factors among HCWs during the first wave of severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) in Madagascar.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective cohort study was carried out in three hospitals that oversaw the first cases of COVID\u201019. Monthly ELISA\u2010based serological tests were conducted, and nasopharyngeal swabs were collected in the case of symptoms linked to COVID\u201019 for RT\u2013PCR analysis. Survival analyses were used to determine factors associated with SARS\u2010CoV\u20102 infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study lasted 7\u00a0months from May 2020. We included 122 HCWs, 61.5% of whom were women. The median age was 31.9\u00a0years (IQR: 26.4\u201342.3). In total, 42 (34.4%) had SARS\u2010CoV\u20102 infections, of which 20 were asymptomatic (47.6%). The incidence of SARS\u2010CoV\u20102 infection was 9.3% (95% CI [6.5\u201313.2]) person\u2010months. Sixty\u2010five HCWs presented symptoms, of which 19 were positive by RT\u2013PCR. When adjusted for exposure to deceased cases, infection was more frequent in HCWs younger than 30\u2009years of age (RR\u2009=\u20094.9, 95% CI [1.4\u201317.2]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our results indicate a high incidence of infection with SARS\u2010CoV\u20102 among HCWs, with a high proportion of asymptomatic cases. Young HCWs are more likely to be at risk than others. Greater awareness among young people is necessary to reduce the threat of infection among HCWs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.13022","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T00:19:30Z","timestamp":1656289170000},"page":"994-1003","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["SARS\u2010CoV\u20102 infection rate in Antananarivo frontline health care workers, Madagascar"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3867-6343","authenticated-orcid":false,"given":"Rila","family":"Ratovoson","sequence":"first","affiliation":[{"name":"Institut Pasteur de Madagascar  Antananarivo Madagascar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaja","family":"Raberahona","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire Joseph Raseta Befelatanana  Antananarivo Madagascar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rado","family":"Razafimahatratra","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire Anosiala\u2010Alakamisy  Antananarivo Madagascar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lova","family":"Randriamanantsoa","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Manara\u2010penitra Andohatapenaka  Antananarivo Madagascar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel Harizaka","family":"Andriamasy","sequence":"additional","affiliation":[{"name":"Institut Pasteur de Madagascar  Antananarivo Madagascar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Perlinot","family":"Herindrainy","sequence":"additional","affiliation":[{"name":"Institut Pasteur de Madagascar  Antananarivo 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