{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T17:51:37Z","timestamp":1780077097217,"version":"3.54.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T00:00:00Z","timestamp":1663027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The objective of this study was to test a novel household\u2010based approach to improve late\u2010season influenza vaccine uptake during the 2020\u20132021 season, using Epic's MyChart patient portal messages and\/or interactive voice response telephone calls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was a non\u2010blinded, quality improvement program using a block randomized design conducted among patients from Reliant Medical Group clinics residing in a traditional household (\u22652 individuals clinically active in the Reliant system living at the same address). Households were randomized 1:1:1 into intervention arms: non\u2010tailored communication (messaging based on CDC's seasonal influenza vaccination campaign), tailored communication (comprehensive communication including reinforcement of the importance of influenza vaccination for high\u2010risk individuals), and standard\u2010of\u2010care control. Influenza vaccination during the program was captured via medical records, and the odds of vaccination among communication arms versus the control arm were assessed. A survey assessing influenza vaccination drivers was administered using MyChart.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Influenza vaccination increased by 3.3% during the program period, and no significant differences in vaccination were observed in intervention arms relative to the control arm. Study operationalization faced substantial challenges related to the concurrent COVID\u201019 pandemic. Compared with vaccinated survey respondents, unvaccinated respondents less frequently reported receiving a recommendation for influenza vaccination from their healthcare provider (15.8% vs. 42.3%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) or awareness that vaccination could protect themselves and higher risk contacts (82.3% vs. 92.6%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>No significant effects of the interventions were observed. Survey results highlighted the importance of healthcare provider recommendations and the need for increased education around the benefits of vaccination.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.13041","type":"journal-article","created":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T10:42:56Z","timestamp":1663065776000},"page":"1141-1150","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A novel household\u2010based patient outreach pilot program to boost late\u2010season influenza vaccination rates during the COVID\u201019 pandemic"],"prefix":"10.1111","volume":"16","author":[{"given":"Lloyd","family":"Fisher","sequence":"first","affiliation":[{"name":"Reliant Medical Group  Worcester Massachusetts USA"},{"name":"UMass Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8100-465X","authenticated-orcid":false,"given":"Matthew M.","family":"Loiacono","sequence":"additional","affiliation":[{"name":"Sanofi  Swiftwater Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Payne","sequence":"additional","affiliation":[{"name":"Optum Life Sciences  Eden Prairie Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Kelley","sequence":"additional","affiliation":[{"name":"Optum Life Sciences  Eden Prairie Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Greenberg","sequence":"additional","affiliation":[{"name":"Sanofi  Swiftwater Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Charpentier","sequence":"additional","affiliation":[{"name":"Reliant Medical Group  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candace","family":"Leblanc","sequence":"additional","affiliation":[{"name":"Reliant Medical Group  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devi","family":"Sundaresan","sequence":"additional","affiliation":[{"name":"Reliant Medical Group  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Bancroft","sequence":"additional","affiliation":[{"name":"Optum Life Sciences  Eden Prairie Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8883-2001","authenticated-orcid":false,"given":"Andrea","family":"Steffens","sequence":"additional","affiliation":[{"name":"Optum Life Sciences  Eden Prairie Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misti","family":"Paudel","sequence":"additional","affiliation":[{"name":"Optum Life Sciences  Eden Prairie Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.05.057"},{"key":"e_1_2_9_3_1","unstructured":"Center for Disease Control and Prevention.Estimated influenza illnesses medical visits hospitalizations and death in the United States\u20142019\u20102020 influenza season. 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