{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:24:28Z","timestamp":1777508668337,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100019125","name":"Sorbonne Universit\u00e9","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019125","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002738","name":"Assistance Publique - H\u00f4pitaux de Paris","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Influenza\u2010like illness (ILI) incidence estimates in individuals treated with immunosuppressants and\/or biologics and\/or corticosteroid for an autoimmune or chronic inflammatory disease are scarce. We compared the ILI incidence among immunocompromised population and the general population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We conducted a prospective cohort study during the 2017\u20132018 seasonal influenza epidemic, on the <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/GrippeNet.fr\">GrippeNet.fr<\/jats:ext-link> electronic platform, which allows the collection of epidemiological crowdsourced data on ILI, directly from the French general population. The immunocompromised population were adults treated with systemic corticosteroids, immunosuppressants, and\/or biologics for an autoimmune or chronic inflammatory disease, recruited directly on <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/GrippeNet.fr\">GrippeNet.fr<\/jats:ext-link> and also among patients of the departments of a single university hospital that were asked to incorporate <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/GrippeNet.fr\">GrippeNet.fr<\/jats:ext-link>. The general population consisted of adults reporting none of the above treatments or diseases participating in <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/GrippeNet.fr\">GrippeNet.fr<\/jats:ext-link>. The incidence of ILI was estimated on a weekly basis and compared between the immunocompromised population and the general population, during the seasonal influenza epidemic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 318 immunocompromised patients assessed for eligibility, 177 were included. During the 2017\u20132018 seasonal influenza epidemic period, immunocompromised population had 1.59 (95% CI: 1.13\u20132.20) higher odds to experience an ILI episode, compared to the general population (<jats:italic>N<\/jats:italic>\u2009=\u20095358). An influenza vaccination was reported by 58% of the immunocompromised population, compared to 41% of the general population (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>During a seasonal influenza epidemic period, the incidence of influenza\u2010like illness was higher in patients treated with immunosuppressants, biologics, and\/or corticosteroids for an autoimmune or chronic inflammatory disease, compared to the general population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.13148","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T11:49:13Z","timestamp":1687952953000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Influenza\u2010like illness in individuals treated with immunosuppressants, biologics, and\/or systemic corticosteroids for autoimmune or chronic inflammatory disease: A crowdsourced cohort study, France, 2017\u20132018"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3083-4711","authenticated-orcid":false,"given":"S\u00e9gol\u00e8ne","family":"Greffe","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Ambroise\u2010Par\u00e9 Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP)  Boulogne\u2010Billancourt France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Guerrisi","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, Institut Pierre Louis d'\u00c9pid\u00e9miologie et de Sant\u00e9 Publique (IPLESP)  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9cile","family":"Souty","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, Institut Pierre Louis d'\u00c9pid\u00e9miologie et de Sant\u00e9 Publique (IPLESP)  Paris 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Sant\u00e9\u201d Medical School, Universit\u00e9 de Versailles Saint\u2010Quentin\u2010en\u2010Yvelines Universit\u00e9 Paris Saclay  Montigny\u2010le\u2010Bretonneux France"},{"name":"Universit\u00e9 Paris\u2010Saclay, UVSQ, Inserm U1173, Infection et inflammation, Laboratory of Excellence INFLAMEX  Montigny\u2010Le\u2010Bretonneux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilaria","family":"Padovano","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Ambroise\u2010Par\u00e9 Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP)  Boulogne\u2010Billancourt France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Bourgault","sequence":"additional","affiliation":[{"name":"\u201cSimone Veil \u2013 Sant\u00e9\u201d Medical School, Universit\u00e9 de Versailles Saint\u2010Quentin\u2010en\u2010Yvelines Universit\u00e9 Paris Saclay  Montigny\u2010le\u2010Bretonneux France"},{"name":"Department of Dermatology Ambroise\u2010Par\u00e9 Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP)  Boulogne\u2010Billancourt France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salim","family":"Trad","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ambroise\u2010Par\u00e9 Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP)  Boulogne\u2010Billancourt France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthieu","family":"Ponsoye","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ambroise\u2010Par\u00e9 Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP)  Boulogne\u2010Billancourt France"},{"name":"\u201cSimone Veil \u2013 Sant\u00e9\u201d Medical School, Universit\u00e9 de Versailles Saint\u2010Quentin\u2010en\u2010Yvelines Universit\u00e9 Paris Saclay  Montigny\u2010le\u2010Bretonneux France"},{"name":"Department of Internal Medicine Foch Hospital  Suresnes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eve","family":"Vilaine","sequence":"additional","affiliation":[{"name":"Department of Nephrology Ambroise\u2010Par\u00e9 Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP)  Boulogne\u2010Billancourt France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Debin","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, Institut Pierre Louis d'\u00c9pid\u00e9miologie et de Sant\u00e9 Publique (IPLESP)  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9ment","family":"Turbelin","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, Institut Pierre Louis d'\u00c9pid\u00e9miologie et de Sant\u00e9 Publique (IPLESP)  Paris 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