{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:47:05Z","timestamp":1772160425163,"version":"3.50.1"},"reference-count":43,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T00:00:00Z","timestamp":1692662400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sarajevo Canton in the Federation of Bosnia and Herzegovina has recorded several waves of high SARS\u2010CoV\u20102 transmission and has struggled to reach adequate vaccination coverage. We describe the evolution of infection\u2010 and vaccine\u2010induced SARS\u2010CoV\u20102 antibody response and persistence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted repeated cross\u2010sectional analyses of blood donors aged 18\u201365\u2009years in Sarajevo Canton in November\u2013December 2020 and 2021. We analyzed serum samples for anti\u2010nucleocapsid (anti\u2010N) and anti\u2010spike (anti\u2010S) antibodies. To assess immune durability, we conducted longitudinal analyses of seropositive participants at 6 and 12\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One thousand fifteen participants were included in Phase 1 (November\u2013December 2020) and 1152 in Phase 2 (November\u2013December 2021). Seroprevalence increased significantly from 19.2% (95% CI: 17.2%\u201321.4%) in Phase 1 to 91.6% (95% CI: 89.8%\u201393.1%) in Phase 2. Anti\u2010S IgG titers were significantly higher among vaccinated (58.5%) than unvaccinated infected participants across vaccine products (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), though highest among those who received an mRNA vaccine. At 6\u00a0months, 78\/82 (95.1%) participants maintained anti\u2010spike seropositivity; at 12\u2009months, 58\/58 (100.0%) participants were seropositive, and 33 (56.9%) had completed the primary vaccine series within 6\u00a0months. Among 11 unvaccinated participants who were not re\u2010infected at 12\u2009months, anti\u2010S IgG declined from median 770.1 (IQR 615.0\u20131321.7) to 290.8 (IQR 175.7\u2013400.3). Anti\u2010N IgG antibodies waned earlier, from 35.4% seropositive at 6\u00a0months to 24.1% at 12\u2009months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>SARS\u2010CoV\u20102 seroprevalence increased significantly over 12\u2009months from end of 2020 to end of 2021. Although individuals with previous infection may have residual protection, COVID\u201019 vaccination is vital to strengthening population immunity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.13182","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T21:30:50Z","timestamp":1692739850000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evolution of seroprevalence to SARS\u2010CoV\u20102 in blood donors in Sarajevo Canton, Federation of Bosnia and Herzegovina: Cross\u2010sectional and longitudinal studies"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7611-2162","authenticated-orcid":false,"given":"Sanjin","family":"Musa","sequence":"first","affiliation":[{"name":"Institute for Public Health of the Federation of Bosnia and Herzegovina  Sarajevo Bosnia and Herzegovina"},{"name":"Sarajevo School of Science and Technology 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Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinisa","family":"Skocibusic","sequence":"additional","affiliation":[{"name":"Institute for Public Health of the Federation of Bosnia and Herzegovina  Sarajevo Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mia","family":"Blazevic","sequence":"additional","affiliation":[{"name":"Institute for Public Health of the Federation of Bosnia and Herzegovina  Sarajevo Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seila","family":"Cilovic Lagarija","sequence":"additional","affiliation":[{"name":"Institute for Public Health of the Federation of Bosnia and Herzegovina  Sarajevo Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gorana","family":"Ahmetovic\u2010Karic","sequence":"additional","affiliation":[{"name":"Institute for Transfusion Medicine of the Federation of Bosnia and Herzegovina  Sarajevo Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alma","family":"Ljuca","sequence":"additional","affiliation":[{"name":"Institute for Transfusion Medicine of the Federation of Bosnia and Herzegovina  Sarajevo Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanela","family":"Dostovic\u2010Halilovic","sequence":"additional","affiliation":[{"name":"Institute for Transfusion Medicine of the Federation of Bosnia and Herzegovina  Sarajevo Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rozalija","family":"Nedic","sequence":"additional","affiliation":[{"name":"Institute for Public Health of the Federation of Bosnia and Herzegovina  Sarajevo Bosnia and Herzegovina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Subissi","sequence":"additional","affiliation":[{"name":"World Health Organization  Geneva 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