{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:47:03Z","timestamp":1772160423274,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T00:00:00Z","timestamp":1717459200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>COVID\u201019 may become a seasonal disease. SARS\u2010CoV\u20102 active circulation coupled with vaccination efforts has undoubtedly modified the virus dynamic. It is therefore important investigate SARS\u2010CoV\u20102 dynamic in different groups of population following the course of spatiotemporal variance and immunization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>To investigate SARS\u2010CoV\u20102 clearance in different ethnic groups and the impact of immunization, we recruited 777 SARS\u2010CoV\u20102\u2010positive patients (570 Africans, 156 Caucasians, and 51 Asians). Participants were followed and regularly tested for 2\u2009months until they had two negative tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The vaccination rate was 64.6%. African individuals were less symptomatic (2%), Caucasians (41%) and Asians (36.6%). On average, viral clearance occurred after 10.5\u00a0days. Viral load at diagnosis was inversely correlated with viral clearance (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001). The time of SARS\u2010CoV\u20102 clearance was higher in Africans and Caucasians than in Asians (Dunn's test\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05, respectively). On average, viral clearance occurred within 9.5\u00a0days during the second semester (higher rate of vaccination and SARS\u2010CoV\u20102 exposition), whereas it took 13.6\u00a0days during the first semester (lower rate of vaccination and SARS\u2010CoV\u20102 exposition) (Mann\u2013Whitney\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In conclusion, ethnicity and spatiotemporal changes including SARS\u2010CoV\u20102 exposition and immunization affect SARS\u2010CoV\u20102 clearance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.13238","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T21:35:05Z","timestamp":1717536905000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Time to SARS\u2010CoV\u20102 clearance in African, Caucasian, and Asian ethnic groups"],"prefix":"10.1111","volume":"18","author":[{"given":"Louis Sides","family":"Ndjengue Nson","sequence":"first","affiliation":[{"name":"Service Laboratoire Clinique Aries Medicus  Port\u2010Gentil Gabon"},{"name":"Department of Public Health, Faculty of Health Sciences Kesmonds International University  Bamenda Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniella","family":"Ndombi Delpo Dede","sequence":"additional","affiliation":[{"name":"Service Laboratoire Clinique Aries Medicus  Port\u2010Gentil Gabon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrice","family":"Lotola Mougeni","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 (CERMEL)  Lambarene Gabon"},{"name":"Faculty of Science University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natacha","family":"Bouassa","sequence":"additional","affiliation":[{"name":"Service Laboratoire Clinique Aries Medicus  Port\u2010Gentil Gabon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basma","family":"Bennjakhoukh","sequence":"additional","affiliation":[{"name":"Department of Public Health, Faculty of Health Sciences Kesmonds International University  Bamenda Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Luthi","sequence":"additional","affiliation":[{"name":"Service Laboratoire Clinique Aries Medicus  Port\u2010Gentil 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