{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T10:47:47Z","timestamp":1774435667547,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,11]],"date-time":"2024-02-11T00:00:00Z","timestamp":1707609600000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Healthcare workers (HWs) are at a high risk of exposure to emerging health threats. Following the first wave of the coronavirus disease 2019 pandemic in Cameroon, we explored the presence and persistence of naturally acquired antibodies against severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) and the factors associated with seropositivity in HWs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Staff at two referral hospitals in Yaound\u00e9 or two Health District Hospitals in Obala and Mbalmayo were included in a 6\u2010month prospective cohort analysis or cross\u2010sectional survey, respectively. Seroprevalence and associated factors were determined, and Kaplan\u2013Meier curves and Cox proportional hazards models were used to assess antibody persistence or positive seroconversion over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From August 2020 to March 2021, 426 HWs (median age: 31\u2009years, interquartile range: 27\u201337\u2009years; 66.4% female) were enrolled. The overall seroprevalence of anti\u2010SARS\u2010CoV\u20102 antibodies was 54.0% (95% confidence interval [CI]: 49.1\u201358.8) and was significantly different between study sites (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04). Of the 216 HWs included in the 6\u2010month cohort, 109 (50.5%) HWs were seropositive at inclusion; the probability of persistent antibodies or of becoming seropositive was 93.8% (95% CI: 84.2\u2013100) and 78.9% (95% CI: 61.7\u201388.4), respectively. Seroconversion was associated with study site and occupation but not with infection prevention and control (IPC) practices.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We observed high seroprevalence of SARS\u2010CoV\u20102 antibody and seroconversion among HWs associated with occupational risk. This suggests low compliance to the COVID\u201019 control measures. Continued training and implementation of IPC measures and accelerated preparedness are needed to better tackle future threats.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.13239","type":"journal-article","created":{"date-parts":[[2024,2,11]],"date-time":"2024-02-11T19:28:15Z","timestamp":1707679695000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["High seroprevalence of severe acute respiratory syndrome coronavirus 2 among healthcare workers in Yaound\u00e9, Cameroon after the first wave of Covid\u201019 pandemic and associated factors"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1420-9628","authenticated-orcid":false,"given":"Mathurin Cyrille","family":"Tejiokem","sequence":"first","affiliation":[{"name":"Service d'\u00e9pid\u00e9miologie et de sant\u00e9 publique Centre Pasteur du Cameroun  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermine Abessolo","family":"Abessolo","sequence":"additional","affiliation":[{"name":"Centre Sp\u00e9cialis\u00e9 de Prise en Charge des Patients Covid\u201019 annexe 2 H\u00f4pital Central de Yaound\u00e9  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph Mendimi","family":"Nkodo","sequence":"additional","affiliation":[{"name":"H\u00f4pital Jamot de Yaound\u00e9  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mireille","family":"Ouethy","sequence":"additional","affiliation":[{"name":"H\u00f4pital Jamot de Yaound\u00e9  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georges Bouting","family":"Mayaka","sequence":"additional","affiliation":[{"name":"H\u00f4pital de District d'Obala  Obala Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yannick","family":"Touha","sequence":"additional","affiliation":[{"name":"H\u00f4pital de District d'Obala  Obala Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich Armel","family":"Dikoume","sequence":"additional","affiliation":[{"name":"H\u00f4pital de District de Mbalmayo  Mbalmayo Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jules Brice","family":"Tchatchueng\u2010Mbougua","sequence":"additional","affiliation":[{"name":"Service d'\u00e9pid\u00e9miologie et de sant\u00e9 publique Centre Pasteur du Cameroun  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane Choualeu","family":"Noumbissi","sequence":"additional","affiliation":[{"name":"Service d'\u00e9pid\u00e9miologie et de sant\u00e9 publique Centre Pasteur du Cameroun  Yaound\u00e9 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