{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:47:01Z","timestamp":1772160421786,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T00:00:00Z","timestamp":1711497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["U2GGH002216"],"award-info":[{"award-number":["U2GGH002216"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cameroon was among the most affected African countries during the first wave of the COVID\u201019 pandemic; however, the true prevalence of SARS\u2010CoV\u20102 remains unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From October to December 2020, we conducted a cross\u2010sectional, age\u2010stratified SARS\u2010CoV\u20102 seroepidemiological survey at 30 purposively selected community\u2010based sites across Cameroon's 10 regional capitals, sampling 10,000 individuals aged 5\u2009years or older. We employed a parallel SARS\u2010CoV\u20102 antibody testing algorithm (WANTAI ELISA and Abbott Architect) to improve both the positive predictive value and negative predictive value of seroprevalence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The overall weighted and adjusted seroprevalence of SARS\u2010CoV\u20102 antibodies across the 10 urban capitals of Cameroon was 10.5% (95% CI: 9.1%\u201312.0%) among participants aged \u22655\u2009years. Of the 9332 participants, 730 males (13.1%, 95% CI: 11.5%\u201314.9%) had SARS\u2010CoV\u20102 antibodies compared to 293 females (8.0%, 95% CI: 6.8%\u20149.3%). Among those who reported a comorbidity at the time of testing, 15.8% (95% CI: 12.8%\u201319.4%) were seropositive. We estimated that over 2 million SARS\u2010CoV\u20102 infections occurred in the 10 regional capitals of Cameroon between October and December 2020, compared to 21,160 cases officially reported at that time translating to one laboratory\u2010confirmed case being reported for every 110 SARS\u2010CoV\u20102 infections across the 10 urban capitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study's findings point to extensive and under\u2010reported circulation of SARS\u2010CoV\u20102 in Cameroon\u2014an almost 100\u2010fold more cases compared to the number of cases reported to the World Health Organization. This finding highlights the importance of conducting serosurveys, especially in settings where access to testing may be limited and to repeat such surveys as part of pandemic tracking.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.13267","type":"journal-article","created":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T03:14:15Z","timestamp":1711509255000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Seroprevalence of SARS\u2010CoV\u20102 in 10 Regional Capitals of Cameroon, October\u2013December 2020"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4451-0561","authenticated-orcid":false,"given":"Karampreet","family":"Sachathep","sequence":"first","affiliation":[{"name":"ICAP at Columbia University  New York New York USA"},{"name":"Department of Population and Family Health Mailman School of Public Health, Columbia University  New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen T.","family":"Duong","sequence":"additional","affiliation":[{"name":"ICAP at Columbia University  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giles","family":"Reid","sequence":"additional","affiliation":[{"name":"ICAP at Columbia University  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily Kainne","family":"Dokubo","sequence":"additional","affiliation":[{"name":"US Centers for Disease Control and Prevention  Atlanta Georgia USA"},{"name":"US Centers for Disease Control and Prevention  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith D.","family":"Shang","sequence":"additional","affiliation":[{"name":"US Centers for Disease Control and Prevention  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clement B.","family":"Ndongmo","sequence":"additional","affiliation":[{"name":"US Centers for Disease Control and Prevention  Atlanta Georgia USA"},{"name":"US Centers for Disease Control and Prevention  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekali","family":"Gabriel","sequence":"additional","affiliation":[{"name":"ICAP in Cameroon  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Tharp","sequence":"additional","affiliation":[{"name":"Department of Sociomedical Sciences Mailman School of Public Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura Eno","family":"Dimite","sequence":"additional","affiliation":[{"name":"US Centers for Disease Control and Prevention  Yaound\u00e9 Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adama","family":"N'Dir","sequence":"additional","affiliation":[{"name":"US Centers for Disease Control 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