{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:20:46Z","timestamp":1790824846990,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:00:00Z","timestamp":1710806400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The emergence of SARS\u2010CoV\u20102 Omicron variant has led to a complete reconfiguration of the therapeutic landscape, with all monoclonal antibodies having lost any neutralization activity. We report here a case series of 75 immunocompromised patients infected by the Omicron variant who benefited from COVID\u201019 convalescent plasma (CCP). At Day 28, the overall survival was 76% (95% CI 67\u201386) with no significant difference in the clinical outcome between patients with hematological malignancies, solid organ transplantation or autoimmune diseases. No safety concern was reported during the course of the study. These results showed that CCP is well tolerated and represents a treatment option for immunocompromised patients who remain highly impacted by the COVID19 epidemic.<\/jats:p>","DOI":"10.1111\/irv.13272","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T06:02:56Z","timestamp":1710828176000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Convalescent Plasma Therapy in Immunocompromised Patients Infected With the BA.1 or BA.2 Omicron SARS\u2010CoV\u20102"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4962-6405","authenticated-orcid":false,"given":"Quentin","family":"Richier","sequence":"first","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"De\u00a0Valence","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doroth\u00e9e","family":"Chopin","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Gras","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"},{"name":"Sorbonne Universit\u00e9, IPLESP, Inserm UMR\u2010S1136  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura I.","family":"Levi","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"},{"name":"Sorbonne Universit\u00e9, IPLESP, Inserm UMR\u2010S1136  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmine","family":"Abi\u00a0Aad","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Pacanowski","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Luc","family":"Meynard","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9o","family":"Pla\u00e7ais","sequence":"additional","affiliation":[{"name":"D\u00e9partement de M\u00e9decine Interne et Immunologie clinique H\u00f4pital Bic\u00eatre  Le Kremlin\u2010Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doroth\u00e9e","family":"Fey","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscille","family":"Couture","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne H\u00f4pital Foch  Suresnes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Martin\u2010Blondel","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales Centre Hospitalier Universitaire de Toulouse  Toulouse France"},{"name":"INSERM UMR1043, Centre de Physiopathologie de Toulouse\u2010Purpan  Toulouse France"},{"name":"Facult\u00e9 de M\u00e9decine Universit\u00e9 de Toulouse Paul Sabatier  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Pestre","sequence":"additional","affiliation":[{"name":"Service de m\u00e9decine interne et maladies infectieuses Centre hospitalier Avignon  Avignon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliette","family":"Woessner","sequence":"additional","affiliation":[{"name":"Service de m\u00e9decine interne et maladies infectieuses Centre hospitalier Avignon  Avignon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Ancellin","sequence":"additional","affiliation":[{"name":"Centre hospitalier d'Auch  France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Weyrich","sequence":"additional","affiliation":[{"name":"Unit\u00e9 d'Infectiologie, Groupement des H\u00f4pitaux Catholiques de Lille, F\u201059160  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Carpentier","sequence":"additional","affiliation":[{"name":"Unit\u00e9 d'Infectiologie, Groupement des H\u00f4pitaux Catholiques de Lille, F\u201059160  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim","family":"Idri","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Tiberghien","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"},{"name":"UMR 1098 RIGHT Inserm Universit\u00e9 de Franche\u2010Comt\u00e9, Etablissement Fran\u00e7ais du Sang  Besan\u00e7on France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Surgers","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"},{"name":"Sorbonne Universit\u00e9, IPLESP, Inserm UMR\u2010S1136  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Hueso","sequence":"additional","affiliation":[{"name":"Service d'h\u00e9matologie clinique, H\u00f4pital Avicenne, APHP, Sorbonne Universit\u00e9 Paris\u2010Nord  Bobigny France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine","family":"Lacombe","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses H\u00f4pital Saint\u2010Antoine, AP\u2010HP  Paris France"},{"name":"Sorbonne Universit\u00e9, IPLESP, Inserm UMR\u2010S1136  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.827242"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2107934"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2116620"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-04389-z"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2119657"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2021.1799"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-022-01511-6"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01540-1"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30483-7"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13279"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26626"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-021-01193-2"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.14089"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.6002\/ect.2020.0479"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020008423"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41385\u2010021\u201000464\u2010w"}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.13272","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T21:44:59Z","timestamp":1711403099000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.13272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1111\/irv.13272"],"URL":"https:\/\/doi.org\/10.1111\/irv.13272","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/IRV.13272\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.13272\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.13272\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.13272\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.13272\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.13272\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.13272\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.13272\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.13272\/v1\/review2","asserted-by":"object"}]},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"value":"1750-2640","type":"print"},{"value":"1750-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"2023-03-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13272"}}