{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:25:06Z","timestamp":1753878306168,"version":"3.41.2"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T00:00:00Z","timestamp":1718928000000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019717","name":"AstraZeneca Espa\u00f1a","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019717","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>During the 2022\u201323 season, three autonomous communities recommended influenza vaccination for all children between 6 and 59\u2009months. The objective is to evaluate the adverse effects associated with the administered influenza vaccines in the Region of Murcia, as well as their influence on the recommendation of the same to acquaintances or repetition in future seasons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Cross\u2010sectional descriptive study with an online questionnaire sent to the parents of vaccinated minors of 6\u201323\u2009months of age receiving inactivated intramuscular vaccine (IIV) or 24\u201359\u2009months of age receiving live\u2010attenuated intranasal vaccine (LAIV).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 4971 surveys received, the most common adverse effect for LAIV and IIV was runny nose (40.90%) and local pain (31.94%), respectively. Sixty percent of adverse effects lasted \u2264 1\u2009day, and around 10% lasted \u2265\u20093\u2009days. The interference of adverse effects with the minor's daily life was very infrequent (3.32%), as was the need for visiting the medical office (2.68%). Overall, 96.44% of parents would recommend influenza vaccination to friends and relatives after the experience. Only 3.56% would not recommend it, while 1.68% would not vaccinate their child against influenza again. The most frequently cited reason being adverse effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study shows the safety of influenza vaccines. Despite the low impact of adverse effects, they influence some parents in their intention to continue vaccinating or recommending it to acquaintances, which remarks the need to reinforce the information given to parents so that this fact does not influence decision\u2010making.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.13331","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T11:59:58Z","timestamp":1718971198000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Adverse Effects Related to Paediatric Influenza Vaccination and Its Influence on Vaccination Acceptability. The FLUTETRA Study: A Survey Conducted in the Region of Murcia, Spain"],"prefix":"10.1111","volume":"18","author":[{"given":"Matilde","family":"Zornoza\u00a0Moreno","sequence":"first","affiliation":[{"name":"Prevention and Health Protection Service Ministry of Health  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaime\u00a0Jes\u00fas","family":"P\u00e9rez\u00a0Mart\u00edn","sequence":"additional","affiliation":[{"name":"Prevention and Health Protection Service Ministry of Health  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda\u00a0Cruz","family":"G\u00f3mez\u00a0Moreno","sequence":"additional","affiliation":[{"name":"Prevention and Health Protection Service Ministry of Health  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda\u00a0del\u00a0Carmen","family":"Valc\u00e1rcel\u00a0G\u00f3mez","sequence":"additional","affiliation":[{"name":"Prevention and Health Protection Service Ministry of Health  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"P\u00e9rez\u00a0Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Prevention and Health Protection Service Ministry of Health  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisca\u00a0Isabel","family":"Tornel\u00a0Mi\u00f1arro","sequence":"additional","affiliation":[{"name":"Prevention and Health Protection Service Ministry of Health  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,21]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Seasonal Influenza \u201cWorld Health Organization \u201d (2023) https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/influenza\u2010(seasonal)."},{"issue":"47","key":"e_1_2_11_3_1","first-page":"461","article-title":"Vaccines Against Influenza WHO Position Paper \u2010 November 2012","volume":"87","year":"2012","journal-title":"Weekly Epidemiological Record"},{"volume-title":"ECDC Scientific Advice on Seasonal Influenza Vaccination of Children and Pregnant Women","year":"2012","key":"e_1_2_11_4_1"},{"key":"e_1_2_11_5_1","unstructured":"\u201cRecommended Immunization for Influenza: European Centre for Disease Prevention and Control \u201dhttp:\/\/vaccine\u2010schedule.ecdc.europa.eu\/Pages\/Scheduler.aspx."},{"key":"e_1_2_11_6_1","unstructured":"C.Delgado\u2010Sanz J.Oliva C.Mazagatos A.Larrauri F.Pozo I.Casas \u201cInforme de Vigilancia de la Gripe en Espa\u00f1a. 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Ponencia de Programa y Registro de Vacunaciones 2022 Sistema Nacional de Salud \u201d (2022) https:\/\/www.sanidad.gob.es\/areas\/promocionPrevencion\/vacunaciones\/programasDeVacunacion\/docs\/Recomendaciones_vacunacion_gripe_PoblacionInfantil.pdf."},{"key":"e_1_2_11_9_1","unstructured":"\u201cVacunaci\u00f3n antigripal en poblaci\u00f3n pedi\u00e1trica sana de 6 a 59 meses de edad \u201d Temporada 2022\u20132023 (2022) https:\/\/www.murciasalud.es\/recursos\/ficheros\/510141\u2010Protocolo_Campana_de_gripe_pediatrico_v2_2022\u20102023v2.pdf."},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anpede.2022.11.002"},{"key":"e_1_2_11_11_1","unstructured":"\u201cSummary of the Prodcut Characteristics. Fluenz Tetra\u00ae\u201d."},{"key":"e_1_2_11_12_1","unstructured":"\u201cSummary of the Product Characteristics. Influvac Tetra\u00ae\u201d."},{"key":"e_1_2_11_13_1","article-title":"Febrile Seizures","volume":"2014","author":"Mewasingh L. 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