{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:47:06Z","timestamp":1772160426028,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T00:00:00Z","timestamp":1717545600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001713","name":"European and Developing Countries Clinical Trials Partnership","doi-asserted-by":"publisher","award":["RIA2020EF\u20103005\u2010MozCOVID"],"award-info":[{"award-number":["RIA2020EF\u20103005\u2010MozCOVID"]}],"id":[{"id":"10.13039\/501100001713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1126780"],"award-info":[{"award-number":["OPP1126780"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mozambique was one of many African countries with limited testing capacity for SARS\u2010CoV\u20102. Serosurveys, an alternative to estimate the real exposure to understand the epidemiology and transmission dynamics, have been scarce in Mozambique. Herein, we aimed to estimate the age\u2010specific seroprevalence of SARS\u2010CoV\u20102 in the general population of the Manhi\u00e7a District, at four time points, for evaluating dynamics of exposure and the impact of vaccination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted four community\u2010based seroepidemiological surveys separated by 3\u2009months between May 2021 and June 2022 to assess the prevalence of SARS\u2010CoV\u20102 antibodies. An age\u2010stratified (0\u201319, 20\u201339, 40\u201359, and \u2265\u200960\u2009years) sample of 4810 individuals was randomly selected from demographic surveillance database, and their blood samples were analyzed using WANTAI SARS\u2010CoV\u20102 IgG\u2009+\u2009IgM ELISA. Nasopharyngeal swabs from a subsample of 2209 participants were also assessed for active infection by RT\u2010qPCR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>SARS\u2010CoV\u20102 seroprevalence increased from 27.6% in the first survey (May 2021) to 63.6%, 91.2%, and 91.1% in the second (October 2021), third (January 2022), and fourth (May 2022) surveys, respectively. Seroprevalence in individuals &lt;\u200918\u2009years, who were not eligible for vaccination, increased from 23.1% in the first survey to 87.1% in the fourth. The prevalence of active infection was below 10.1% in all surveys.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A high seroprevalence to SARS\u2010CoV\u20102 was observed in the study population, including individuals not eligible for vaccination at that time, particularly after circulation of the highly transmissible Delta variant. These data are important to inform decision making on the vaccination strategies in the context of pandemic slowdown in Mozambique.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.13332","type":"journal-article","created":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T04:15:22Z","timestamp":1717560922000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["High SARS\u2010CoV\u20102 Exposure in Rural Southern Mozambique After Four Waves of COVID\u201019: Community\u2010Based Seroepidemiological Surveys"],"prefix":"10.1111","volume":"18","author":[{"given":"\u00c1uria","family":"de Jesus","sequence":"first","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o em Sa\u00fade de Manhi\u00e7a (CISM)  Maputo Mozambique"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Ernesto","sequence":"additional","affiliation":[{"name":"Centro de Investiga\u00e7\u00e3o em Sa\u00fade de 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