{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:47:09Z","timestamp":1790790429811,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T00:00:00Z","timestamp":1730678400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["CK17\u20101701"],"award-info":[{"award-number":["CK17\u20101701"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["CK24\u20102401"],"award-info":[{"award-number":["CK24\u20102401"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["NU38OT000297\u201002\u201000"],"award-info":[{"award-number":["NU38OT000297\u201002\u201000"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Screening for SARS\u2010CoV\u20102 infection among hospital admissions made interpretation of COVID\u201019 hospitalization data challenging as SARS\u2010CoV\u20102\u2013positive persons with mild or asymptomatic infection may be incorrectly identified as COVID\u201019\u2013associated hospitalizations. The study objective is to estimate the proportion of hospitalizations likely attributable to COVID\u201019 among SARS\u2010CoV\u20102\u2013positive hospitalized patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A sample of laboratory\u2010confirmed SARS\u2010CoV\u20102\u2013positive hospitalizations from the COVID\u201019\u2013Associated Hospitalization Surveillance Network (COVID\u2010NET) from June 2020 to September 2023 was analyzed, with a focus on July 2022 to September 2023. Likely COVID\u201019\u2013attributable hospitalizations were defined as hospitalizations among SARS\u2010CoV\u20102\u2013positive non\u2010pregnant adults ages \u2265\u200918\u2009years with COVID\u201019\u2013related presenting complaint, treatment, or discharge diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 44,816 sampled hospitalizations, 90% met the definition of likely COVID\u201019\u2013attributable. Among the 9866 admissions occurring during July 2022 to September 2023, 86% were likely COVID\u201019\u2013attributable; 87% had a COVID\u201019\u2013related presenting complaint, 64% received steroids or COVID\u201019\u2013related treatment, 47% had respiratory\u2010 and 10% had coagulopathy\u2010related discharge diagnoses, and 39% had COVID\u201019 as the principal discharge diagnosis code. More than 70% met \u2265\u20092 criteria. Compared with likely COVID\u201019\u2013attributable hospitalizations, SARS\u2010CoV\u20102\u2013positive patients who did not meet the case definition were more likely to be ages 18\u201349\u2009years (27% vs. 13%), have no underlying medical conditions (14% vs. 4%), or be asymptomatic for COVID\u201019 upon admission (46% vs. 10%) (all <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Most hospitalizations among SARS\u2010CoV\u20102\u2013positive adults in a recent period were likely attributable to COVID\u201019. COVID\u201019\u2013attributable hospitalizations are less common among younger SARS\u2010CoV\u20102\u2013positive hospitalized adults but still account for nearly three quarters of all admissions among SARS\u2010CoV\u20102\u2013positive adults in this age group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/irv.70021","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T03:55:09Z","timestamp":1730778909000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Trends in COVID\u201019\u2013Attributable Hospitalizations Among Adults With Laboratory\u2010Confirmed SARS\u2010CoV\u20102\u2014COVID\u2010NET, June 2020 to September 2023"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0937-5461","authenticated-orcid":false,"given":"Christopher\u00a0A.","family":"Taylor","sequence":"first","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Whitaker","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica\u00a0E.","family":"Patton","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"},{"name":"United States Public Health Service Commissioned Corps  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3243-9854","authenticated-orcid":false,"given":"Michael","family":"Melgar","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pam\u00a0Daily","family":"Kirley","sequence":"additional","affiliation":[{"name":"California Emerging Infections Program  Oakland California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Breanna","family":"Kawasaki","sequence":"additional","affiliation":[{"name":"Colorado Department of Public Health &amp; Environment  Denver Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Yousey\u2010Hindes","sequence":"additional","affiliation":[{"name":"Connecticut Emerging Infections Program Yale School of Public Health  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle\u00a0P.","family":"Openo","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine  Atlanta Georgia USA"},{"name":"Georgia Emerging Infections Program, Georgia Department of Public Health  Atlanta Georgia USA"},{"name":"Atlanta Veterans Affairs Medical Center  Decatur Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia\u00a0A.","family":"Ryan","sequence":"additional","affiliation":[{"name":"Maryland Department of Health  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Kim","sequence":"additional","affiliation":[{"name":"Michigan Department of Health and Human Services  Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Como\u2010Sabetti","sequence":"additional","affiliation":[{"name":"Minnesota Department of Health  St. Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic","family":"Solhtalab","sequence":"additional","affiliation":[{"name":"New Mexico Emerging Infections Program  Albuquerque New Mexico USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant","family":"Barney","sequence":"additional","affiliation":[{"name":"New York State Department of Health  Albany New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda\u00a0L.","family":"Tesini","sequence":"additional","affiliation":[{"name":"University of Rochester School of Medicine and Dentistry  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy\u00a0E.","family":"Moran","sequence":"additional","affiliation":[{"name":"Ohio Department of Health  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Sutton","sequence":"additional","affiliation":[{"name":"Public Health Division Oregon Health Authority  Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u00a0Keipp","family":"Talbot","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Olsen","sequence":"additional","affiliation":[{"name":"Salt Lake County Health Department  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona\u00a0P.","family":"Havers","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"},{"name":"United States Public Health Service Commissioned Corps  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0241536"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14057"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.100789"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.11.044"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.2730"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.13089"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6938e1"},{"key":"e_1_2_10_9_1","unstructured":"COVID\u201019 Treatment Guidelines Panel \u201cCoronavirus Disease 2019 (COVID\u201019) Treatment Guidelines \u201d National Institutes of Health."},{"key":"e_1_2_10_10_1","unstructured":"Centers for Medicare & Medicaid Services (U.S.) National Center for Health Statistics (U.S.).ICD\u201010\u2010CM Official Guidelines for Coding and Reporting FY 2023 \u2010\u2010 UPDATED April 1 2023 (October 1 2022 \u2010 September 30 2023).2023."},{"key":"e_1_2_10_11_1","unstructured":"M.Hill \u201cAlmost half of Mass \u201d COVID Hospitalizations Are Now Classified as \u2018Incidental.\u2019 Here's What That Means. Boston Globe Media Partners https:\/\/www.boston.com\/news\/coronavirus\/2022\/01\/21\/almost\u2010half\u2010of\u2010mass\u2010covid\u2010hospitalizations\u2010are\u2010now\u2010classified\u2010as\u2010incidental\u2010heres\u2010what\u2010that\u2010means\/."},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2196\/37931"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7137a4"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2024.3"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7240a3"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7111e2"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7107e4"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010023\u201033569\u20102"}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.70021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T08:44:14Z","timestamp":1732610654000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.70021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/irv.70021"],"URL":"https:\/\/doi.org\/10.1111\/irv.70021","archive":["Portico"],"relation":{},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"value":"1750-2640","type":"print"},{"value":"1750-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"2024-05-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70021"}}