{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:47:04Z","timestamp":1772160424343,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T00:00:00Z","timestamp":1731456000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>RSV bronchiolitis is a leading cause of hospitalization in infants and young children. We aimed to document the economic burden and epidemiology of RSV over seven seasons in Southern Austria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>All RSV\u2010associated hospitalized (PCR\u2010proven) children \u2264\u20095\u2009years of age between 1 October 2015 and 30 April 2022 were collected retrospectively. Demographic and epidemiologic data, along with hospitalization costs (direct and indirect), were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 976 children hospitalized due to RSV infection, 87% were healthy term infants, and 79% were &lt;\u200912\u2009months old. Prematurity (13%) and pre\u2010existing conditions (11%) significantly impacted older children\u201459% of cases in the 2nd compared with 68% in the 1st year of live. RSV\u2010related hospital costs were approximately \u20ac2.0 millions per year (of a total of 60 millions per year). RSV accounted for 19% of hospitalizations due to acute respiratory illness (ARI) in children \u2264\u20095\u2009years, 37% of all ARI\u2009&lt;\u20096\u2009months, 28% of all ARI\u2009&lt;\u200912 and 6.3% of all\u2010cause hospitalizations &lt;\u200912\u2009months of age, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Every 5th hospitalization due to respiratory illness in children \u2264\u20095\u2009years of age was associated with RSV, representing 7.9% of all hospitalizations and 3.3% of all paediatric hospitalization costs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.70046","type":"journal-article","created":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T22:00:02Z","timestamp":1731535202000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Evaluating the Economic and Epidemiological Impact of RSV Hospitalizations in Southern Austria [Southern Austria Respiratory Syncytial Virus INpatient Investigation (ARNI Study)]"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2562-2960","authenticated-orcid":false,"given":"G.","family":"Sever\u00a0Yildiz","sequence":"first","affiliation":[{"name":"Research Unit for Neonatal Infectious Diseases and Epidemiology Medical University of Graz  Graz Austria"},{"name":"Department of Paediatrics and Adolescent Medicine, Division of General Paediatrics Medical University of Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Resch","sequence":"additional","affiliation":[{"name":"Research Unit for Neonatal Infectious Diseases and Epidemiology Medical University of Graz  Graz Austria"},{"name":"Department of Paediatrics and Adolescent Medicine, Emergency Room Medical University of Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Strenger","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, Division of General Paediatrics Medical University of Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Eber","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, Division of Paediatric Pulmonology and Allergology Medical University of Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Resch","sequence":"additional","affiliation":[{"name":"Research Unit for Neonatal Infectious Diseases and Epidemiology Medical University of Graz  Graz Austria"},{"name":"Department of Paediatrics and Adolescent Medicine, Division of Neonatology Medical University of Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(22)00478"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874285801105010144"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.5409\/wjcp.v1.i3.8"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0804877"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002494"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010021\u201006399\u20108"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2023.03.024"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2003.036129"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010022\u201007745\u20100"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00608\u2010019\u201000725\u20109"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/a\u20100868\u20100004"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199311183292102"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiac216"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/CEOR.S382495"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.880368"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000535"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916\u2010023\u201002854\u20102"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz683"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiad188"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2022.09.003"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1824\u20107288\u201040\u201065"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010021\u201006544\u20103"}],"container-title":["Influenza 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