{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T08:34:27Z","timestamp":1782462867809,"version":"3.54.5"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012319","name":"National Center for Global Health and Medicine","doi-asserted-by":"publisher","award":["19K059"],"award-info":[{"award-number":["19K059"]}],"id":[{"id":"10.13039\/100012319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012319","name":"National Center for Global Health and Medicine","doi-asserted-by":"publisher","award":["21A2013D"],"award-info":[{"award-number":["21A2013D"]}],"id":[{"id":"10.13039\/100012319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012319","name":"National Center for Global Health and Medicine","doi-asserted-by":"publisher","award":["23A2020D"],"award-info":[{"award-number":["23A2020D"]}],"id":[{"id":"10.13039\/100012319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012319","name":"National Center for Global Health and Medicine","doi-asserted-by":"publisher","award":["24A1011"],"award-info":[{"award-number":["24A1011"]}],"id":[{"id":"10.13039\/100012319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The impact of the simultaneous circulation of COVID\u201019 and seasonal influenza, termed the \u201cTwindemic,\u201d on absenteeism among healthcare workers (HCWs), particularly those with children, remains unclear. We aimed to investigate the associations of living with school\u2010aged children with the risk of SARS\u2010CoV\u20102 and influenza infections and the risk of absenteeism due to own\u2010 or family\u2010related COVID\u201019 or influenza events among HCWs during the Twindemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective study followed 1473 HCWs at a tertiary hospital in Tokyo from December 2023 to March 2024. We tracked the incidence of SARS\u2010CoV\u20102 and influenza infections and absenteeism due to COVID\u201019 or influenza\u2010related family events. We estimated the hazard ratios (HRs) or incidence rate ratios (IRRs) of these outcomes across living arrangements, focusing on cohabitation with school\u2010aged children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>HCWs living with younger school\u2010aged children (\u2264\u2009third grade of junior school) had a higher risk of SARS\u2010CoV\u20102 and influenza infections, with HRs [95% confidence interval (CI)] of 1.90 [0.97\u20133.69] and 2.42 [1.04\u20135.66], respectively, compared with those living with cohabitants without school\u2010aged children. Additionally, they showed a higher IRR [95% CI] for absenteeism due to family\u2010related events (10.9 [4.88\u201324.5]), and their overall IRR [95% CI] of absenteeism due to own\/family\u2010related events was 3.76 [2.59\u20135.46].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The Twindemic has heightened absenteeism risks among HCWs with school\u2010aged children, emphasizing the need for targeted support to help HCWs manage both their professional duties and family responsibilities during such challenging times.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.70100","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:46:33Z","timestamp":1745541993000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Living With School\u2010Aged Children and the Risk of Absenteeism Among Healthcare Workers During the Twindemic of COVID\u201019 and Influenza"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6503-8577","authenticated-orcid":false,"given":"Shohei","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Prevention Center for Clinical Sciences, Japan Institute for Health Security  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1198-2228","authenticated-orcid":false,"given":"Tetsuya","family":"Mizoue","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Prevention Center for Clinical Sciences, Japan Institute for Health Security  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maki","family":"Konishi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Prevention Center for Clinical Sciences, Japan Institute for Health Security  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumi","family":"Horii","sequence":"additional","affiliation":[{"name":"Infection Control Office National Center for Global Health and Medicine, Japan Institute for Health Security  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wataru","family":"Sugiura","sequence":"additional","affiliation":[{"name":"Center for Clinical Sciences Japan Institute for Health Security  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4622-8970","authenticated-orcid":false,"given":"Norio","family":"Ohmagari","sequence":"additional","affiliation":[{"name":"Disease Control and Prevention Center Japan Institute for Health Security  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,21]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"World Health Organization \u201cGlobal Influenza Programme \u2013 FluNet \u201d Accessed May 15 2024 https:\/\/www.who.int\/tools\/flunet."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2020.10.021"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19020769"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-021-07200-x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2021.04.018"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40273-022-01224-9"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-022-03175-8"},{"key":"e_1_2_10_9_1","first-page":"684","article-title":"Risk Factors of Influenza Transmission in Households","volume":"54","author":"Viboud C.","year":"2004","journal-title":"British Journal of General Practice"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2022.08.003"},{"key":"e_1_2_10_11_1","unstructured":"National Institute of Infection Diseases \u201cInfectious Disease Weekly Report JAPAN (IDWR) \u201d Available at:https:\/\/www.niid.go.jp\/niid\/en\/idwr\u2010e.html. Accessed January 15 2025."},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268823000353"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofae455"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2021-321604"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2022.05.016"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2015.10.012"}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.70100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T09:31:29Z","timestamp":1748338289000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.70100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/irv.70100"],"URL":"https:\/\/doi.org\/10.1111\/irv.70100","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/IRV.70100\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.70100\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.70100\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.70100\/v2\/decision1","asserted-by":"object"}]},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"value":"1750-2640","type":"print"},{"value":"1750-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2024-08-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70100"}}