{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T19:45:36Z","timestamp":1783626336431,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004339","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004339","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We previously reviewed methods for estimating the timing of respiratory syncytial virus (RSV) epidemics. This study examines the impact of various estimation methods on determining the start, end, duration, and capture rate of RSV epidemics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We applied eight estimation methods to RSV surveillance data from the Global Epidemiology of RSV (GERi) study, covering Chile, New Zealand, Singapore, South Africa, Spain, and the United States: 3% and 10% positivity rate, moving epidemic method (MEM), mean positivity, 1.2% total detections, mean and 60% mean number, and 75% average annual percentage (AAP). We compared the median start, end, duration, and capture rate of RSV epidemics obtained from these methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Within countries, the median duration of RSV epidemics varied by over 10\u2009weeks, and the median capture rates ranged from &gt; 95 to &lt; 60%, depending on the estimation method. Generally, the 3% positivity rate method identified the longest RSV epidemics (earliest median start and latest end, and highest capture rate). The 10% positivity rate, MEM, and 75% AAP methods indicated the shortest RSV epidemics with the lowest capture rate. The remaining four methods produced intermediate results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings underscore the importance of selecting estimation methods suited to the surveillance system and the intended use, whether for outbreak alert, planning, or targeted interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.70123","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:54:53Z","timestamp":1748825693000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluating the Impact of Different Methods on the Timing and Duration of RSV Epidemics: Analysis of Surveillance Data From the GERi (Global Epidemiology of RSV in Hospitalized and Community Care) Study"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6985-3541","authenticated-orcid":false,"given":"Lisa","family":"Staadegaard","sequence":"first","affiliation":[{"name":"Netherlands Institute for Health Services Research (Nivel)  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Del\u00a0Riccio","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Health Services Research (Nivel)  Utrecht The Netherlands"},{"name":"Department of Health Sciences University of Florence  Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7267-0897","authenticated-orcid":false,"given":"Susanne","family":"Heemskerk","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Health Services Research (Nivel)  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7746-053X","authenticated-orcid":false,"given":"Michel","family":"D\u00fcckers","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Health Services Research (Nivel)  Utrecht The Netherlands"},{"name":"Faculty of Behavioral and Social Sciences University of Groningen  Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo\u00a0A.","family":"Fasce","sequence":"additional","affiliation":[{"name":"Subdepartment of Viral Diseases Public Health Institute of Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Bustos","sequence":"additional","affiliation":[{"name":"Respiratory and Exanthematic Virus Section Public Health Institute of Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3923-5195","authenticated-orcid":false,"given":"Q.\u00a0Sue","family":"Huang","sequence":"additional","affiliation":[{"name":"Institute of Environmental Science and Research  Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0376-2302","authenticated-orcid":false,"given":"Cheryl","family":"Cohen","sequence":"additional","affiliation":[{"name":"Centre for Respiratory Disease and Meningitis National Institute for Communicable Diseases  Johannesburg South Africa"},{"name":"School of Public Health, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn","family":"Moyes","sequence":"additional","affiliation":[{"name":"Centre for Respiratory Disease and Meningitis National Institute for Communicable Diseases  Johannesburg South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vernon\u00a0Jian\u00a0Ming","family":"Lee","sequence":"additional","affiliation":[{"name":"Ministry of Health  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0036-255X","authenticated-orcid":false,"given":"Li\u00a0Wei","family":"Ang","sequence":"additional","affiliation":[{"name":"Ministry of Health  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Monge","sequence":"additional","affiliation":[{"name":"National Centre of Epidemiology Institute of Health Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Mart\u00ednez\u2010Pino","sequence":"additional","affiliation":[{"name":"Public Health Directorate Castilla y Le\u00f3n Regional Ministry of Health  Valladolid Spain"},{"name":"CIBER Epidemiology and Public Health (CIBERESP), Institute of Health Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Bangert","sequence":"additional","affiliation":[{"name":"Health Economics &amp; Value Assessment Vaccines Sanofi Vaccines  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Kramer","sequence":"additional","affiliation":[{"name":"Health Economics &amp; Value Assessment Vaccines Sanofi Vaccines  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1503-2481","authenticated-orcid":false,"given":"John","family":"Paget","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Health Services Research (Nivel)  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Foekje\u00a0F.","family":"Stelma","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Health Services Research (Nivel)  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jojanneke","family":"van Summeren","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Health Services Research (Nivel)  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2262-1102","authenticated-orcid":false,"given":"Saverio","family":"Caini","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Health Services Research (Nivel)  Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)00478-0"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23570"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/322657"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40121-016-0123-0"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(19)30264-5"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12885"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy056"},{"issue":"5","key":"e_1_2_9_9_1","first-page":"17","article-title":"Seasonality and Geographical Spread of Respiratory Syncytial Virus Epidemics in 15 European Countries, 2010 to 2016","volume":"23","author":"Broberg E. K.","year":"2018","journal-title":"Euro Surveillance"},{"key":"e_1_2_9_10_1","unstructured":"European Medicines Agency.Synagis\u2014Summary of Product Characteristics accessed May 26 2024 Online at:https:\/\/www.ema.europa.eu\/en\/documents\/product\u2010information\/synagis\u2010epar\u2010product\u2010information_en.pdf."},{"key":"e_1_2_9_11_1","unstructured":"European Medicines Agency.Beyfortus Nirsevimab. Summary of Opinion (Initial Authorisation)15 September 2022. EMA\/CHMP\/647784\/2022. Committee for Medicinal Products for Human use (CHMP). accessed May 26 2024 Online at:https:\/\/www.ema.europa.eu\/en\/documents\/smop\u2010initial\/chmp\u2010summary\u2010positive\u2010opinion\u2010beyfortus_en.pdf."},{"key":"e_1_2_9_12_1","unstructured":"CDC.Respiratory Syncytial Virus Infection (RSV). RSV Immunization Guidance for Infants and Young Children accessed October 20 2024 Online at:https:\/\/www.cdc.gov\/rsv\/hcp\/vaccine\u2010clinical\u2010guidance\/infants\u2010young\u2010children.html#:~:text=The%20optimal%20timing%20for%20nirsevimab ideally%20during%20the%20birth%20hospitalization."},{"key":"e_1_2_9_13_1","unstructured":"Arexvy.European Medicines Agency (EMA) accessed May 26 2024 Online at:https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/arexvy."},{"key":"e_1_2_9_14_1","unstructured":"European Medicines Agency (EMA).Abrysvo accessed May 26 2024 Online at:https:\/\/www.ema.europa.eu\/en\/medicines\/human\/summaries\u2010opinion\/abrysvo."},{"issue":"5","key":"e_1_2_9_15_1","article-title":"Determining the Timing of Respiratory Syncytial Virus (RSV) Epidemics: A Systematic Review, 2016 to 2021; Method Categorisation and Identification of Influencing Factors","volume":"29","author":"Staadegaard L.","year":"2024","journal-title":"Euro Surveillance"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12779"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix275"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2019.09.010"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2019.24.20.1800469"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofab159"},{"key":"e_1_2_9_21_1","unstructured":"U.S. Department of Health and Human Services (HHS).HHS Regional Offices. Regional Map accessed August 31 2024 Online at:https:\/\/www.hhs.gov\/about\/agencies\/iea\/regional\u2010offices\/index.html."},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7214a1"},{"key":"e_1_2_9_23_1","unstructured":"National Cancer Institute. Division of Cancer Control & Population Sciences.Joinpoint Trend Analysis Software accessed May 26 2024 Online at:https:\/\/surveillance.cancer.gov\/joinpoint\/."},{"key":"e_1_2_9_24_1","unstructured":"J. E.Lozano T.Vega.The Moving Epidemic Method. The MEM Web Application: Technical Manual accessed September 4 2024 Online at:https:\/\/github.com\/lozalojo\/memapp."},{"key":"e_1_2_9_25_1","unstructured":"World Bank DataBank.World Development Indicators accessed November 6 2024 Online at:https:\/\/databank.worldbank.org\/source\/world\u2010development\u2010indicators."},{"key":"e_1_2_9_26_1","unstructured":"United Nations Development Programme (UNDP).Annual Report 2021 accessed November 6 2024 Online at:https:\/\/www.undp.org\/publications\/undp\u2010annual\u2010report\u20102021."},{"key":"e_1_2_9_27_1","unstructured":"World Bank DataBank.Demographics accessed November 6 2024 Online at:https:\/\/databank.worldbank.org\/databases\/demographics."}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.70123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T22:32:11Z","timestamp":1751495531000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.70123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/irv.70123"],"URL":"https:\/\/doi.org\/10.1111\/irv.70123","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/IRV.70123\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.70123\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.70123\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.70123\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.70123\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/IRV.70123\/v1\/review2","asserted-by":"object"}]},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"value":"1750-2640","type":"print"},{"value":"1750-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-01-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70123"}}