{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:30:53Z","timestamp":1777984253428,"version":"3.51.4"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:00:00Z","timestamp":1769817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:00:00Z","timestamp":1769817600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005744","name":"Lastentautien Tutkimuss\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005744","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007083","name":"Orionin Tutkimuss\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007083","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008309","name":"Hengityssairauksien Tutkimuss\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008309","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Male sex is a well\u2010known risk factor for respiratory syncytial virus (RSV) hospitalization in children, but there are no data on potential differences in clinical features between boys and girls hospitalized with RSV infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We compared the average population\u2010based rates of hospitalization and the clinical features of the illness between boys and girls hospitalized with virologically confirmed RSV infection during 2006\u20132020 at Turku University Hospital, Finland. During this period, testing for RSV was routine in all children admitted with respiratory infections. The comparisons were performed in different age groups of children up to 5\u2009years of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among all 1204 children &lt;\u20095\u2009years of age hospitalized with RSV, the average annual RSV hospitalization rates were 4.0\/1000 in boys and 3.3\/1000 in girls (incidence rate ratio [IRR] 1.21; 95% CI, 1.07\u20131.35;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). The difference was greatest in children aged 3\u201323\u2009months, among whom the corresponding rates were 5.4\/1000 in boys and 3.6\/1000 in girls (IRR, 1.50; 95% CI, 1.25\u20131.80;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The occurrence of respiratory distress was consistently higher in boys than in girls among children aged 6\u201317\u2009months. In this group of 233 children, 128 of 141 (90.8%) boys had documented respiratory distress, compared with 70 of 92 (76.1%) girls (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Except for the first 3\u2009months after birth, boys have a 50% higher risk of RSV hospitalization than girls during the first 2\u2009years of life. In that same age group, boys hospitalized with RSV have also significantly more respiratory distress than girls.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.70235","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T08:56:26Z","timestamp":1769849786000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Hospitalization Rates and Clinical Features Between Boys and Girls With Respiratory Syncytial Virus Infection"],"prefix":"10.1111","volume":"20","author":[{"given":"Erika","family":"Uusitupa","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Turku and Turku University Hospital  Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matti","family":"Waris","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology Turku University Hospital  Turku Finland"},{"name":"Institute of Biomedicine University of Turku  Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tytti","family":"Vuorinen","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology Turku University Hospital  Turku Finland"},{"name":"Institute of Biomedicine University of Turku  Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terho","family":"Heikkinen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Turku and Turku University Hospital  Turku 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