{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:52:25Z","timestamp":1792097545855,"version":"4.4.0"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:00:00Z","timestamp":1772582400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Human adenoviruses (HAdV) circulate globally, but their seasonal patterns remain poorly defined. We aimed to characterize the timing, amplitude, and duration of HAdV epidemics worldwide and to compare patterns before and after the COVID\u201019 pandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Virological surveillance data on HAdV were obtained from the WHO FluNet database: data from 65 countries were analyzed to estimate epidemic peak timing, amplitude, and duration across the Northern and Southern Hemispheres and the intertropical belt, comparing prepandemic (2016\u20132019) with postpandemic (2021\u20132024) periods. To ensure robustness, analyses were restricted to country\u2010seasons with \u2265\u200930 reporting weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From 2016 to 2024, 65 countries reported roughly 148,000 HAdV detections across 335 country\u2010seasons; 46% of seasons had \u2265\u200950 detections. In the 20 countries with sufficient data for seasonality analyses, median epidemic duration was 31\u2009weeks (range 5\u201342) and median peak amplitude 70% (40%\u201398%). Peak timing followed latitude: June\u2013July in Southern Hemisphere, November\u2013December in high\u2010latitude Northern countries, March\u2013April in lower latitude. After COVID\u201019, several countries showed marked timing shifts, with concurrent changes in amplitude.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>After the onset of the COVID\u201019 pandemic, the usual seasonal patterns of HAdV were altered, with pronounced shifts in peak timing across settings and latitudes. These results underscore the need for strong, ongoing, type\u2010specific surveillance to guide public health strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.70236","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T20:29:59Z","timestamp":1773001799000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Global Epidemiology of Human Adenoviruses, 2016\u20132024: A Pre\u2010 and Post\u2010COVID\u201019 Analysis of Circulation Patterns and Epidemic Timing"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6368-9316","authenticated-orcid":false,"given":"Emma","family":"Papini","sequence":"first","affiliation":[{"name":"Department of Health Sciences University of Florence  Florence 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Health Sciences University of Florence  Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Saviozzi","sequence":"additional","affiliation":[{"name":"Department of Health Sciences University of Florence  Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8202-2937","authenticated-orcid":false,"given":"Patrizio","family":"Zanobini","sequence":"additional","affiliation":[{"name":"Department of Health Sciences University of Florence  Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saverio","family":"Caini","sequence":"additional","affiliation":[{"name":"University of Florence  Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Del\u00a0Riccio","sequence":"additional","affiliation":[{"name":"Department of Health Sciences University of Florence  Florence 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