{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T21:03:16Z","timestamp":1788901396762,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","award":["70109063"],"award-info":[{"award-number":["70109063"]}],"id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Quantifying the burden of respiratory syncytial virus (RSV) in adults is challenging compared to influenza, and data among older adults remain scarce in Japan. Country\u2010specific evidence is essential to support RSV vaccination policy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective, multicenter study (APSG\u2010J2) targeted hospitalized adults with community\u2010acquired pneumonia (CAP) and other acute respiratory infections (ARI) in seven community hospitals across four catchment areas in Japan between September 2022 and August 2024. Respiratory samples were analyzed using a multiplex polymerase chain reaction (PCR) kit to detect RSV and influenza. Incidence rates of RSV\u2010 and influenza\u2010associated hospitalizations were estimated using study data and national statistics, stratified by age and region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 3047 hospitalized patients with CAP\/ARI, 1499 (49.2%) underwent multiplex PCR testing. RSV and influenza were detected in 2.8% and 3.3% of tested patients, respectively. The incidences of RSV\u2010associated CAP\/ARI hospitalizations among adults aged \u2265\u200965\u2009years were 29 and 36 per 100,000 person\u2010years in the first and second years, respectively, with higher incidences among those aged \u2265\u200985\u2009years (150 and 131 per 100,000 person\u2010years). Influenza incidence increased markedly in the second year (from 11 to 71 per 100,000 person\u2010years for adults age \u2265\u200965\u2009years), possibly reflecting post\u2010COVID\u201019 transmission changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this multicenter study, we estimated the incidence of RSV\u2010 and influenza\u2010associated hospitalizations among adults in Japan. The findings indicated that the incidence increased with age, and influenza\u2010associated hospitalizations increased in the second year. Continued surveillance is essential to accurately assess RSV burden in the adult population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.70238","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T03:18:51Z","timestamp":1773631131000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Incidence of RSV\u2010 and Influenza\u2010Associated Hospitalizations With Community\u2010Acquired Pneumonia and Other Acute Respiratory Infection Among Adults in Japan in 2022\u20132024: APSG\u2010J2 Study"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0014-2602","authenticated-orcid":false,"given":"Haruka","family":"Maeda","sequence":"first","affiliation":[{"name":"Department of Respiratory Infections, Institute of Tropical Medicine Nagasaki University  Nagasaki 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