{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T10:34:56Z","timestamp":1774521296911,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The extent of cross\u2010reactive antibodies to SARS\u2010CoV\u20102 elicited by seasonal human coronaviruses (HCoVs) remains unclear. We analyzed longitudinal preinfection and postinfection IgG responses in 62 older adults with PCR\u2010confirmed HCoV infections from sera collected prior to the emergence of SARS\u2010CoV\u20102. At baseline, 12.9% and 16.1% had low\u2010titer antibodies against SARS\u2010CoV\u20102 spike (S) or nucleocapsid (N) proteins, respectively, but postinfection increases were marginal. Our findings suggest seasonal HCoV infections induce limited SARS\u2010CoV\u20102 cross\u2010reactive antibodies in community\u2010dwelling older adults.<\/jats:p>","DOI":"10.1111\/irv.70250","type":"journal-article","created":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T06:36:30Z","timestamp":1773470190000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cross\u2010Reactive IgG Antibody Responses to SARS\u2010CoV\u20102 in Older Adults Following Seasonal Coronavirus Infection in Jiangsu, China (2015\u20132017)"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9245-5995","authenticated-orcid":false,"given":"Cheng","family":"Xiao","sequence":"first","affiliation":[{"name":"HKU\u2010Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy\u00a0H.\u00a0L.","family":"Leung","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiman","family":"Ling","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Respiratory Diseases Guangzhou Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xia","family":"Lin","sequence":"additional","affiliation":[{"name":"HKU\u2010Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuyun","family":"Chen","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanmin","family":"Xie","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malik","family":"Peiris","sequence":"additional","affiliation":[{"name":"School of Public Health, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Zanin","sequence":"additional","affiliation":[{"name":"School of Public Health, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"},{"name":"Center for Infection and Immunology Hong Kong Science Park  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6297-7154","authenticated-orcid":false,"given":"Benjamin","family":"Cowling","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1290-191X","authenticated-orcid":false,"given":"Sook\u2010San","family":"Wong","sequence":"additional","affiliation":[{"name":"HKU\u2010Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2020.104490"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abe1107"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2021.12.005"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI143380"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.156372"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23074-3"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa322"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-017503"},{"key":"e_1_2_11_10_1","doi-asserted-by":"crossref","unstructured":"N. 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