{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T14:36:13Z","timestamp":1786545373184,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The 8th International Society for Respiratory Viruses (ISRV) Antiviral Group Conference, held jointly with the 3rd International Meeting on Respiratory Pathogens in Singapore (17\u201320 September 2025), examined evolving approaches to prevention and management of respiratory infections. This report summarizes the major themes and perspectives that emerged across the meeting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We reviewed plenary sessions, thematic symposia and panel discussions and synthesized recurring concepts relevant to clinical practice and preparedness. Discussions were organized into key domains, including therapeutics, host response, vaccination, surveillance, diagnostics and research infrastructure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Presentations highlighted the development of long\u2010acting and broadly active antivirals, interest in combination therapy and early treatment, and increasing recognition that inflammatory host responses contribute substantially to disease severity. Advances in vaccines targeting conserved viral components and long\u2010acting monoclonal antibodies were discussed, along with the growing role of adaptive platform trials and harmonized clinical endpoints. A recurring theme was the transition from pathogen\u2010centred management to a broader framework incorporating host responses. Speakers also emphasized integrated surveillance using genomic sequencing, metagenomics and rapid point\u2010of\u2010care diagnostics within a One Health framework addressing zoonotic spillover.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The meeting illustrated how clinical care, translational science and public health preparedness are becoming increasingly interconnected. Sustained investment in surveillance systems, clinical trial platforms and access to therapeutics will be necessary to translate scientific progress into routine care and to strengthen readiness for future epidemics and pandemics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.70276","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T06:41:09Z","timestamp":1782456069000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Navigating the Future of Respiratory Infections: Key Insights From International Congress in Singapore, 17\u201320 September 2025"],"prefix":"10.1111","volume":"20","author":[{"given":"Narmadha","family":"Morvil","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Singapore General Hospital  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilson Guo Wei","family":"Goh","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases National University Hospital  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases National Centre for Infectious Diseases  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Sutjipto","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases National Centre for Infectious Diseases  Singapore"},{"name":"Department of Infectious Diseases Tan Tock Seng Hospital  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0917-1474","authenticated-orcid":false,"given":"Dorothy Hui Lin","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Singapore General Hospital  Singapore"},{"name":"Programme in Emerging Infectious Diseases Duke\u2010NUS Medical School  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8897-7881","authenticated-orcid":false,"given":"Maria","family":"Zambon","sequence":"additional","affiliation":[{"name":"Respiratory Virus Unit (RVU) UK Health Security Agency  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"key":"e_1_2_14_2_1","unstructured":"MSD \u201cMSD to Complete Acquisition of Cidara Therapeutics \u201d (2026) https:\/\/www.msd.com\/news\/msd\u2010to\u2010complete\u2010acquisition\u2010of\u2010cidara\u2010therapeutics\/."},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1716197"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30004-9"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2024.10.020"},{"key":"e_1_2_14_6_1","unstructured":"K.Andreev S.D\u00f6hrmann J.Levin et\u00a0al. \u201cA Single Prophylactic Dose of CD388 Provides Protection Against Highly Pathogenic Bovine\u2010Origin Influenza A(H5N1) Virus in the Ferret Model [Oral Presentation] \u201d 3rd International Meeting on Respiratory Pathogens (IMRP) 2025 Singapore (September 2025)."},{"key":"e_1_2_14_7_1","unstructured":"R.Bright N.Davarpanah C. 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