{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:41:39Z","timestamp":1791265299126,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Respiratory syncytial virus (RSV) is a major cause of hospitalizations in young children and older adults in the United States. Monitoring seasonal RSV activity through national surveillance systems and understanding the relationships among RSV surveillance indicators can help ensure timely administration of prevention products and improve preparedness among healthcare systems and public health programs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed RSV data across six surveillance years from the National Respiratory and Enteric Virus Surveillance System (NREVSS), National Syndromic Surveillance Program (NSSP), commercial laboratories, New Vaccine Surveillance Network (NVSN), and Respiratory Syncytial Virus Hospitalization Surveillance Network (RSV\u2010NET). We characterized RSV seasonality and compared pediatric and all\u2010age surveillance indicators (percent positivity, percentage of ED visits, and hospitalization rates) at key points during the RSV season. We then estimated cross\u2010correlations and lags between each system and NREVSS before, during, and after the COVID\u201019 pandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Five RSV seasons occurred between 2018 and 2024. Pediatric indicators were greater than all\u2010age indicators at NREVSS season onset (range: 1.4\u20136.3 times greater), peak (1.3\u20135.8), and offset (1.1\u20134.7). Nationally, indicators were highly correlated across systems (\n                      <jats:italic>\u03c1<\/jats:italic>\n                      \u2009&gt;\u20090.92) during the prepandemic and postdisruption periods, with minimal lags (0\u20131\u2009weeks). However, correlations (\n                      <jats:italic>\u03c1<\/jats:italic>\n                      = 0.48\u20130.99) and lags (0\u20136\u2009weeks) varied across regions and time windows during these periods.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pediatric surveillance indicators provide the earliest indications of RSV season onset. CDC systems that provide complementary data on RSV activity and associated outcomes are highly correlated at the national and regional levels but may not capture local trends that are important for optimizing prevention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.70284","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T08:02:35Z","timestamp":1783584155000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Correlations and Timeliness of Respiratory Syncytial Virus Surveillance Indicators\u2014United States, 2018\u20132024"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1364-0025","authenticated-orcid":false,"given":"Erin L.","family":"Anderson","sequence":"first","affiliation":[{"name":"Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7056-511X","authenticated-orcid":false,"given":"Erica Billig","family":"Rose","sequence":"additional","affiliation":[{"name":"Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber","family":"Winn","sequence":"additional","affiliation":[{"name":"Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0570-8628","authenticated-orcid":false,"given":"Sophia","family":"Chkonia","sequence":"additional","affiliation":[{"name":"Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Moline","sequence":"additional","affiliation":[{"name":"Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariana","family":"Toepfer","sequence":"additional","affiliation":[{"name":"Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica E.","family":"Patton","sequence":"additional","affiliation":[{"name":"Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0937-5461","authenticated-orcid":false,"given":"Christopher A.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Kite\u2010Powell","sequence":"additional","affiliation":[{"name":"Office of Public Health Data, Surveillance, and Technology Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Dietz","sequence":"additional","affiliation":[{"name":"Office of Public Health Data, Surveillance, and Technology Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sheppard","sequence":"additional","affiliation":[{"name":"Office of Public Health Data, Surveillance, and Technology Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jourdan","family":"DeVies","sequence":"additional","affiliation":[{"name":"Office of Public Health Data, Surveillance, and Technology Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin J.","family":"Silk","sequence":"additional","affiliation":[{"name":"Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,9]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Centers for Disease Control and Prevention Coronavirus and Other Respiratory Viruses Division National Center for Immunization and Respiratory Diseases \u201cPreliminary 2024\u20132025 U.S. RSV Burden Estimates \u201d accessed December 12 2025 https:\/\/www.cdc.gov\/rsv\/php\/surveillance\/burden\u2010estimates.html."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7332e1"},{"key":"e_1_2_10_4_1","unstructured":"Centers for Disease Control and Prevention \u201cRSV Vaccine Guidance for Adults. Updated July 8 2025 \u201d accessed November 13 2025 https:\/\/www.cdc.gov\/rsv\/hcp\/vaccine\u2010clinical\u2010guidance\/adults.html."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7234a4"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7241e1"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7432a3"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(20)30703\u20109"},{"issue":"48","key":"e_1_2_10_9_1","first-page":"1133","article-title":"Respiratory Syncytial Virus \u2010 United States, July 2012\u2013June 2014","volume":"63","author":"Haynes A. K.","year":"2012","journal-title":"MMWR. Morbidity and Mortality Weekly Report"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix275"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6702a4"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000090921.21313.d3"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7029a1"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7214a1"},{"key":"e_1_2_10_15_1","unstructured":"MMWR Week Overview \u201cNational Notifiable Diseases Surveillance System Division of Health Informatics and Surveillance Epidemiology and Laboratory Services \u201d accessed July 29 2025 https:\/\/ndc.services.cdc.gov\/wp\u2010content\/uploads\/MMWR_week_overview.pdf2025."},{"key":"e_1_2_10_16_1","unstructured":"Centers for Disease Control and Prevention \u201cAbout NSSP. Updated July 7 2025 \u201d accessed November 13 2025 https:\/\/www.cdc.gov\/nssp\/php\/about\/."},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.44756"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lana.2025.101166"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318157da82"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2014.3804"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/SMJ.0b013e318048589e"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318157dac1"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318157daae"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciae140"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201047757\u20109"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S396434"},{"key":"e_1_2_10_27_1","unstructured":"Association of Immunization Managers 2025\u20102026 Respiratory Syncytial Virus (RSV) Monoclonal Antibody (mAb) Season Extension Map accessed June 8 2026 https:\/\/www.immunizationmanagers.org\/resources\/2025\u20102026\u2010respiratory\u2010syncytial\u2010virus\u2010rsv\u2010monoclonal\u2010antibody\u2010mab\u2010season\u2010extension\u2010map\/."}],"container-title":["Influenza and Other Respiratory Viruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.70284","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/irv.70284","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/irv.70284","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T13:40:16Z","timestamp":1786542016000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/irv.70284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/irv.70284"],"URL":"https:\/\/doi.org\/10.1111\/irv.70284","archive":["Portico"],"relation":{},"ISSN":["1750-2640","1750-2659"],"issn-type":[{"value":"1750-2640","type":"print"},{"value":"1750-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70284"}}